After more than four years on hormone therapy and 6 rounds of chemo, my dad's PSA is beginning to slowly rise. It has moved from .07 size months ago to .13 three months ago to .23 today.
He has been on Lupron and casodex for the past four plus years. Can anyone give me any insight into what we should expect? Will his oncologist suggest that he drops the casodex for its antagonistic behaviors? Will we continue to monitor the PSA since the rise is not doubling? Should we expect another scan? Which drug is it will be on the horizon next? Zytiga? Erleada? Provenge? Any insight you may have is greatly appreciated!
Also, when my dad was diagnosed his PSA was 257 with only a single lymph node outside the prostate impacted. Since he is considered oligo metastatic, would targeted radiation be a viable treatment option?
I will watch the behavior of PSA more before making conclusion that Lupron has failed.
I would like to check PSA every two weeks and chart the pattern. If it clearly shows a steady upward trend for 2 -3 months, I will assume that Lupron has failed. Just my opinion.