human beast milk as a cancer therapy? - Advanced Prostate...

Advanced Prostate Cancer

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human beast milk as a cancer therapy?

sammamish profile image
9 Replies

Came across this article, sounded intriguing. A molecule found in human breast milk apparently has anti-tumor effects in vitro. A protein called "Hamlet" apparently.

sciencefocus.com/news/compo...

independent.co.uk/life-styl...

Anyone have any knowledge on this topic?

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sammamish profile image
sammamish
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9 Replies
sammamish profile image
sammamish

and also this pubmed article

ncbi.nlm.nih.gov/pubmed/310...

Patrick-Turner profile image
Patrick-Turner

Hmm, finding a wet nurse to let you drink from her breast might be difficult.

Maybe a marrow transplant from Germaine Greer might work better,

but side effects could be that any male features you have, including Pca, would all be exterminated in hours, and you turn into a grumpy old sheila.

Good luck pursuing these lines of attack on Pca....

Patrick Turner.

pjoshea13 profile image
pjoshea13

About a dozen years ago I came across a guy with PCa who was convinced that human milk would help him. He was able to get milk from a milk bank for a while, but ultimately located a woman who would pump for him. I don't know how that ultimately worked out. Perhaps he is in this group?

I thought it was crazy to be getting a daily dose of IGF-I. Milk is the only food that comes with a growth hormone.

But what about HAMLET - which is not actually a component of milk?

The story goes back 20 years [1]:

"In this study alpha-lactalbumin was converted from the regular, native state to a folding variant with altered biological function. The folding variant was shown to induce apoptosis in tumor cells and immature cells, but healthy cells were resistant to this effect. Conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells) required partial unfolding of the protein and a specific fatty acid, C18:1, as a necessary cofactor. Conversion was achieved with alpha-lactalbumin derived from human milk whey and with recombinant protein expressed in Escherichia coli. We thus have identified the folding change and the fatty acid as two key elements that define HAMLET, the apoptosis-inducing functional state of alpha-lactalbumin. Although the environment in the mammary gland favors the native conformation of alpha-lactalbumin that serves as a specifier in the lactose synthase complex, the conditions under which HAMLET was formed resemble those in the stomach of the nursing child."

No human trials so far.

***

Incidentally, Dr. Myers has warned about colostrum [2]:

-Patrick

[1] ncbi.nlm.nih.gov/pubmed/107...

[2] askdrmyers.wordpress.com/20...

j-o-h-n profile image
j-o-h-n

“Though this be madness, yet there is method in't.”

― William Shakespeare, Hamlet

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 08/12/2019 4:48 PM DST

in reply to j-o-h-n

to suckle or not to suckle, that is the question ...

j-o-h-n profile image
j-o-h-n in reply to

Let us eat Ham...

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 08/12/2019 8:18 PM DST

monte1111 profile image
monte1111

Dolly with real, live action human milk dispensing nipples. Should sell like hot cakes. Sorry, this item is on back order.

j-o-h-n profile image
j-o-h-n in reply to monte1111

Put me down for two...include the hot cakes....

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 08/12/2019 8:31 PM DST

Got milk? Hamlet ? Go ice cream...

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