I came across the following news article on a new promising therapy to treat breast and prostate cancer using magnets made by soil bacteria and viruses that specifically attack cancer cells:
Interesting approach for directing oncolytic viruses to a tumor. They use en external magnetic over the tumor site to draw the magnetized virus to it.
I think that could work for a local tumor in the prostate, or a few metastases, but not if there were many metastases diffusely spread throughout the body. There may be some way to do it that I haven't thought of.
It seems that most of the current advances are about targeting the tumor with treatment and avoiding other healthy tissue. I think when the tumor is local to the prostate it's much easier to target physically. Cryoablation, SBRT, radiation seeds all are physically targeted treatments. It seems that injecting oncovirusrs directly into the tumor using MRI guiding would also work.
Once it becomes metastatic, a systemic targeting method, such as antigen targeting of radiopharmacueticals, small molecules are T cells are needed to find the diffuse and possibly undetected sites.
In my mind, I have the same question. In Brachytherapy low or high dose radiation implants are placed close inside the body or right next to the cancer cells. Why not inject the virus right into the tumors guided by MRI or other scanning mechanisms?Do any of the experts on this forum have an answer? Thanks.
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