PSA jumped post SRT

[ken12491]

PSA jumped to 1.25 from 0.48 in 5 weeks as did my T levels, was 329 now at 421 with a PSA at 1.25. Is this to be expected? I 've been off ADT since 2/18 Last shot - a 3-month shot ) Is there an alternative to lupron with fewer side effects?

[NPfisherman]

Usually--a PSA is done 6 weeks post radiation--but I doubt that the trend is your friend. Talk with your RO and get a referral to Johns Hopkins Radiology because they are doing the Ga68 PSMA scan (closest to NY that I am aware of) and that could tell you where the biochemical recurrence is coming from inside you. Did you have adjuvant radiation? You had an RP as I recall. Once you know where the tumor(s) is, then figuring out a treatment gets easier... and can be used to re-evaluate success post treatment

ncbi.nlm.nih.gov/pmc/articl...

Best of luck....

Fish

[ken12491 in reply to NPfisherman]

thanks, and yes, I did have ADT ( Lupron ) from 5/2/17 to 2/18 (3-month dosage ) so it was a total of 1 yrs lupron was in my body. Under the care now of a MO, same hospital, SMK..

[NPfisherman in reply to ken12491]

The adjuvant radiation is whole pelvic radiation--done with ADT...Did you have that or salvage radiation? The success with adjuvant is higher. I think you mean MSK--Memorial Sloan Kettering. I would get the Ga68PSMA scan--get with an RO and make decisions based on that information. Best of luck...

Fish

[Tall_Allen]

The first PSA after SRT should be in 3 months because cells are still dying from the radiation, dumping their PSA into your bloodstream.

[Johnstonearch]

I have been onLupron for 20 years continuously. Now the side effects seem like normal life.

[ken12491]

wow!!! great for you and u overcame as I will too should they tell me that's what I should be doing...wish u continued success. saw ur profile, was your dx stage 4, 20 yrs ago? did u have RP, SRT or just Lupron?

[j-o-h-n]

Ok ken, admit it you're fooling around with Barbie again...in West Hurley, NY.

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 07/18/2019 8:08 PM DST