Five weeks ago, started adjunctive ADT in prep for HDR Brachy in a few weeks. Scholz at POS recommended Casodex, Lupron, and Zytiga together. Due to delays in approvals, and whatnot, the first 3 weeks I was on Casodex alone, dropped PSA from 33 to 21. Then added Zytiga+Pred for last two weeks, and PSA dropped to 4 on just 3/4 dosage of 3x250mg (my choice to ramp up). Haven’t had a Lupron shot yet and T measured < 10. I’m tolerating Z very well so far, no major SE’s, ALT and ALP are elevated slightly over ULN.
So the question is, should I even bother with Lupron since T is negligible, and PSA has dropped 86% in 5 weeks?