Wondering what is next?

[Kobina]

Diagnosed 6/15/17 gleason7 psa 89 lots of bone Mets started Bicalutamide 6/15/17 for 1 month then Lupron, zytiga(Abiraterone) Prednisone 2x a day, and Zometa, in July 18 had Mets to base of skull had 10 radiation treatments. Keep on same meds December 15 had bone scan and CT scan was told Zytiga stopped working because of more bone Mets. Pain in hip and outside rectum so 10 treatments radiation. PSA rising slightly so put on zXtandi (Enzalutamide) still on Lupron, Zometa. Stopped eating about 3 weeks after going on Enz says everything tastes awful and really salty. Lost 12 lbs in 15 days finally have the weight loss under control with Boost still doesn’t eat much. He was onGabapentin for hot flashes but quit taking it in March says they are no worse than with it. He is now on Oxycodone 2 pills every 4 hours during the day, 12 hour release Morphine at night, Tamsulosin 2x a day, Ondansetron 2x a day. Is going to have Bone scan and CT this month to see if Xtandi is working but I think that is causing the bad taste in his mouth so I will ask dr. At his app. on the 25

So what’s next?

He does not feel good most of the time so yes it is consuming our life. Not complaint just wish he felt better. (He is not a positive person) so it make me down too.

Thank you for this site.

[YostConner]

Sounds like it’s worth asking the doc about radium 223.

[CalBear74]

Kobina, These comments of mine might sound negative but here are a few things that struck me as a non-physician.

1. Send the biopsy samples to Jonathan Epstein, MD, Ph.D. at John's Hopkins for a second opinion.. The Gleason 7 needs his confirmation.

2. Your history sounds problematic. I don't know what practical effects the second opinion will have if you stop there, but I wouldn't. Seek out a medical oncologist from Dr. Epstein's colleagues that he recommends and get his/her confirmation of what is going on. I think these are important steps to take quickly. Phone: [phone] in Maryland.

I recently counseled a man who contacted me because of a support group I facilitate. He was told he was a 7 by a west Phoenix, AZ pathologist. I had no special reason to doubt the professional judgment of the pathologist beyond the reputation of the practice he chose to affiliate with (I had spent many years in Phoenix in the health care sector), but as it turned out the patient did seek Dr. Epstein's second opinion and learned he was a Gleason 8 primarily. That can have practical treatment effects.

Good luck,

CalBear74

[j-o-h-n]

Greetings Kobina, would you please be kind enough to give us more info in a future post and NOT to me. age? location? treatment center? doctor's name(s)? All info voluntary. This info helps us help your husband and it help us too. Thank you.

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 04/08/2019 6:35 PM DST