Has anyone seen their PSA go down aft... - Advanced Prostate...

Advanced Prostate Cancer

21,850 members27,367 posts

Has anyone seen their PSA go down after taking boron?

George71 profile image
4 Replies

I read that 10 mg daily reduced PSA

Written by
George71 profile image
George71
To view profiles and participate in discussions please or .
Read more about...
4 Replies
Tall_Allen profile image
Tall_Allen

Be careful about using medicines that reduce PSA - it is an important biomarker - you don't want to screw with it.

George71 profile image
George71

I see where gusgold posted a few months back:

"Researcher At Mayo Clinic Told Me To Take Boron"

and many others here are taking boron -- have any seen a slowing down or drop in PSA?

and how much are you taking?

pjoshea13 profile image
pjoshea13

George,

I use boron.

Here is what I posted in 2016:

healthunlocked.com/advanced...

I would not expect to see a dramatic effect on PSA. PSA is produced as a result of androgen receptor [AR] activity. In general, one would not expect a supplement to artificially reduce PSA without inhibiting AR activity.

-Patrick

Ralph1966 profile image
Ralph1966

Hi Patrick,

Are you using 3mg or 6 mg of Boron daily?

It seems that Boron is helpful at least to delay the progression of prostate cancer:

Read this:

"After only 1 week of boron supplementation of 6 mg/d, a further study by Naghii et al20 of healthy males (n = 8) found (1) a significant increase in free testosterone, which rose from an average of 11.83 pg/mL to 15.18 pg/mL; and (2) significant decreases in E2, which dropped from 42.33 pg/mL to 25.81 pg/mL. All of the inflammatory biomarkers that were measured also decreased: (1) interleukin (IL) 6, from 1.55 pg/mL to 0.87 pg/mL; (2) high-sensitivity C-reactive protein (hs-CRP) by approximately 50%, a remarkable decrease, from 1460 ng/mL to 795 ng/mL; and (3) tumor necrosis factor α (TNF-α) by approximately 30%, from 12.32 to 9.97 pg/mL. Levels of dihydrotestosterone, cortisol, and vitamin D increased slightly.

The significant decrease in the men’s plasma E2 after 1 week of boron supplementation suggests a higher rate of conversion of total testosterone (T) to free testosterone (FT) in the testosterone metabolic pathway. In support, the ratios of FT/T, T/E2, and FT/E2 were all significantly increased, indicating boron had androgen amplifier effects: (1) FT/T (pg/mL/ng/mL) increased from 3.62 to 4.66; (2) T/E2 (ng/mL) rose from 91.68 to 148; and (3) FT/E2 (ng/mL) from 0.31 to 0.67".

Source: ncbi.nlm.nih.gov/pmc/articl...

I am thinking to take 6 mg of boron daily for 7-10 days prior to my next PSA test and see the results. I didn't find any negative effect or bad effect as for the progression or worsening of prostate cancer for people who take Boron daily.

Not what you're looking for?

You may also like...

has anyone seen this?

https://news.stanford.edu/2022/10/03/breakthrough-production-acclaimed-cancer-treating-drug/

How long does PSA stay down after chemo?

Just finished my tenth session of taxotere. It dropped my PSA over 80% to under 5 and my alk Phos...

Has anyone had their genetic testing change over time?

My husband tested PTEN loss in his first genetic tests when tissue was taken from his RP in mid...

1 Year after taking Zytiga (Abiraterone) PSA from 750 to 54

Hello everyone. Id like to post update on my fathers therapy. This time last year he got the...

Has anyone seen testosterone rise on xtandi while still on lupron?

Just wondering if anyone else has seen there testosterone go up above castrate level after starting...