Muscles cramp and spasm more at night - Advanced Prostate...

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Muscles cramp and spasm more at night

Olivia007 profile image
23 Replies

My dad is on Lupron , Xgeva, zytiga and his other maintenance meds for other conditions he keeps complaining of muscle cramps and tightness in his calf muscles mainly and mostly during the night. Been to doctors no one can seem to help us anyone have same issue and found relief?

Thank u,

Olivia

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Olivia007
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23 Replies
pjoshea13 profile image
pjoshea13

Olivia,

This crops up regularly, although not in the context of a specific PCa treatment.

The first thing to consider is an insufficiency of acetylcholine - a key neurotransmitter. The old remedy is pickle juice. Anything with acetic acid will do. Worth trying first.

But magnesium before bed might help. Some swear by a banana, for the potassium. Etc, etc.

A friend has used quinine for years, but the FDA frowns on that [1]. Besides, I have never heard of a quinine deficiency.

-Patrick

[1] medscape.com/viewarticle/77...

Kimmilemo profile image
Kimmilemo in reply to pjoshea13

Heard the other day for restless legs , thin shavings of ivory soap under the sheets of the calf area , and a teaspoon of yellow mustard. I have no idea but my daughters suffer from it so I’ll let you know.

Kimmilemo profile image
Kimmilemo in reply to Kimmilemo

Oh and I get cramps I put vinegar on a paper towel on the cramp it goes away ASAP.

pjoshea13 profile image
pjoshea13 in reply to Kimmilemo

Yellow mustard contains vinegar, & vinegar itself can be up to 20% acetic acid.

I have no idea what Ivory soap would do.

-Patrick

GranPaSmurf profile image
GranPaSmurf in reply to pjoshea13

But your malaria would be under control... 😉

GoBucks profile image
GoBucks

I drink water before going to bed. I no longer have leg cramps. I was already getting up to pee anyway so who cares if I drink before sleep?

I'm currently on Zytiga and frequently have muscle cramps at night. Making sure you have drank enough water is important.

Low potassium level is a possible side effect of Zytiga. The prednisone is supposed to help with that. I'm also taking a Kalium supplement (potassium). That seems to help. I will be talking to my doctor about it at the next appointment.

tango65 profile image
tango65

They need to study electrolites, particularly potassium, calcium and magnesium. Talk with your doctor. He is in Xgeva which could cause hypocalcemia and in Zytiga which could cause hypokalemia.

noirhole profile image
noirhole

Bananas and keeping hydrated helped me. I feel your pain. My cramps would wake me up from a dead sleep to the moon with the muscle so tight I would have to pound it out. Drinking more water and eating a banana day for several days usually fixed it. Good luck!

huhnes profile image
huhnes

Did he have his blood sugar Checked? When I started my chemo treatment, the doctor said I would likely become diabetic. 14 months later, same symptoms you described. On insulin an metformin. I feel great. Don't fear the needle.

paulofaus profile image
paulofaus

I've read that tissue salts,Mag Phos helps.

donovan0932 profile image
donovan0932

Magnesium citrate should help .I take 1000mg morning and night

Wdoug profile image
Wdoug

My severe cramps lasted about 3 to 4 months at end of ratiation then went away. Now in 3rd year of lupron. Be patient.

mcp1941 profile image
mcp1941

I had occasional leg cramps before starting Zytiga but WOW what excruciating leg cramps while on Zytiga. Tried many things found on the web but nothing worked until I tried Cramp Defense. After two weeks no more cramps. I was only on Zytiga for three more months but I keep taking one pill a day. In the past five years I have had only two mild calf cramps and they were gone in a minute. I hate to give a commercial endorsement on this site but this worked so well for me.

Poscan4 profile image
Poscan4

Does he do a lot of heavy perspiring

Do to the Medications? He may be loosing a lot of electrolytes which will cause muscle crps. I drink G2 Gatorade for this problem plus take Niacin tablets. This helps.

monte1111 profile image
monte1111

Occasional severe calf cramp, usually right leg, at night while sleeping. Have to, very carefully, walk it out. The pickle juice idea seems like a great way to go as a first try. I use to eat up to 3 dill pickle spears a night to help with the sore throat I had during chemo. Didn't have cramps then. Think I'll start having a pickle spear before going to bed. Meds: Lupron, xgeva, celebrex, xtandi, prednisone, and gabapentin.

Stegosaurus37 profile image
Stegosaurus37

Stand up, putting all your weight on the leg with the cramp and it will disappear right away. I eat a banana a day for the extra magnesium; haven't tried pickle juice but sounds like a great idea.

Boywonder56 profile image
Boywonder56

Tonic water has quinine in it...scheps diet...works wonders...the lack of test.is the culprit i have stg 4 and still work const....cramps like sob..so i keep it on hand...they make six pack small bottles...there ar some over counter meds but none have quinine...ck with doc first...just saying

Olivia007 profile image
Olivia007 in reply to Boywonder56

Thank u we r trying that how much do u drink per day? How many ounces?

Boywonder56 profile image
Boywonder56

Atleone small bottle ...

dmt1121 profile image
dmt1121

I am currently not on any treatment and have the occasional leg cramp at night that feels like it will snap my femur. I take supplemental potassium but I drink plenty of water also. I may have not had enough that day though. Massage also helps.

Good luck.

GranPaSmurf profile image
GranPaSmurf

I've had leg cramps for years before the PC diagnosis - the only thing that has helped me is Jigsaw Magnesium - slow release.

jigsawhealth.com/supplement...

Guppyman1773 profile image
Guppyman1773

On Zytiga for 2 months lots of nocturnal leg cramping ..drinking water and standing up for a few minutes is only thing that helps.

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