Age and symptom Dose reduction Xtandi... - Advanced Prostate...

Advanced Prostate Cancer
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Age and symptom Dose reduction Xtandi and Zytiga

mjbach
mjbach

Having just attended a seminar where dose reduction was discussed by Dr. Snuffy Myers I thought others might be interested in his opinion. He had a 104 yo patient who couldn’t tolerate Xtandi full dose. He gradually reduced from one capsule every other day until he died at age 107 when he was taking one Xtandi capsule per week.

This conflicts with our MO advice for my husband to get back to full dose after experiencing a seizure-like episode and fall. We will go with Snuffy’s opinion.

12 Replies
oldestnewest

But the guy was 104! He should not have been taking ANYTHING! The odds of his dying of prostate cancer were minuscule.

mjbach
mjbach
in reply to Tall_Allen

Yes agree. However, it was an amusing anecdote that shows how no matter age or ailment most people prefer living.

HiddenThis reply has been deleted
Tall_Allen
Tall_Allen
in reply to Hidden

Snuffy Myers is just offering his opinion, which is certainly open to question. I hope that patients DO question what they hear from him or anyone else - that's what patient empowerment is all about. Some, like you, evidently, just accept everything you hear as gospel. I advocate a more questioning attitude. NCCN differs and they set the standard of care (not Dr Myers) because they represent a consensus of the top prostate cancer physicians in the US and they rely on research. They advocate watchful waiting when life expectancy is ≤ 5 years:

"Patients with life expectancies ≤5 years with high, very high, regional, and metastatic disease are also candidates for observation if the risks and complications of therapy are judged to be greater than the benefit in terms of prolonged life or improved QOL."

charlesmeyers1964
charlesmeyers1964
in reply to Hidden

sorry dude i totally agree with tall-allen he lived a good life let him go on his own time

Who is Snuffy Myers

Darryl
DarrylAdministrator

No one should extrapolate a conference presented patient treatment case study and apply it to their own treatment without First discussing it with their own doctor. Let me know if this isn’t obvious and I’ll write more on Monday.

first where i do live i don't have confident with these so called oncologists. its sad we in Spokane WA don't have true specialist in cancer of the prostrate they are over 300 miles away and worst if u live out of town from Spokane so a true doctor is what we need for sure.

I drive 4 hours to Seattle to SCCA. I feel it is worth it. Do my Lupron, Chemo and check ups there. I am very pleased with the quality of care.

I was also at the talk Saturday. This patient chose to continue active care, and to work with Dr. Myers on that, which they did. I’m not sure whether the experience of this otherwise apparently physically and mentally healthy gentleman of such unusual age can translate to group data, but it’s important to have all kinds of data on individuals — average and outliers — to understand more fully treatment possibilities.

I read about that 107 year old man... he was shot dead by a jealous husband.

Good Luck and Good Health.

j-o-h-n Monday 10/15/2018 2:24 PM EDT

Brbnbrn
Brbnbrn
in reply to j-o-h-n

😂 Love it!

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