Losing hope
On Lupron an xgeva , failed zytiga an... - Advanced Prostate...
On Lupron an xgeva , failed zytiga and now on xtandi 3 months psa has doubled every month it is up to 900 , but it’s weird it feel better
Has anyone else had pain relief on xtandi but psa rapidly rising?
![charlesmeyers1964 profile image](https://images.hu-production.be/avatars/d8753af618cb433aae7951cd0aa29701_small@2x_100x100.jpg)
i took it briefly but it didn't seem to relieve any of my pain because i had none.
charlie
![Kevinski65 profile image](https://images.hu-production.be/avatars/4ec03d53159f4fb398c917fe1014edac_small@2x_100x100.jpg)
I've been on Xtandi and Lupron. I'm 6 years out. 3 years on Lupron then Xtandi added after that. I'm having pain but PSA 0.02 for the past 3 years. I use aspirin. Bone scans, PET scans, and cat scan shows nothing significant. All 3 bone mets dormant, resolved whatever. I have pain at night in my femers, lower back and neck. It's probably micrometastasis, who knows.
You must get that explosive rise in your PSA under control...Have you done chemo ? Dosetaxel might be the ticket to slow things down and give you some time to develop a new treatment plan..
Not yet probably that’s next
Have you had Xofigo or Provenge?
Yes Provenge about a yr and a half ago
![Tall_Allen profile image](https://images.hu-production.be/avatars/017e665a21f4bd4ca22c6ca88452d433_small@2x_100x100.jpg)
Talk to your oncologist about Xofigo if you have bone mets.
If visceral mets, consider the Lu-177-PSMA randomized clinical trial, now in Omaha, Indianapolis, Mayo Clinic, UCLA, Tulane, Albuquerque, Kettering OH, and Houston (there will be about 30 sites eventually):
clinicaltrials.gov/ct2/show...
Thanks I do have bone mets
Thanks for you imput
The trial that TA mentioned is called "Vision" It's trial number is NCT03511664. They are doing this treatment in patients in Europe and Australia with good results..If you live near one of the locations doing the trial, it would be worth looking into..It's sponsored by a company called Endocyte
u didn't say what your psa is and how long have u had cancer. i've been fighting it now for 10 years. i just finished up a new tx since 2006 PROVENGE. check it out
charlie