My dad was diagnosed with advanced prostate cancer in May 2016. Initial PSA was 25 and Gleason score 9. It was already spread to the bladder. His prostate and bladder was cleaned by an operation. After the operation he was given hormone-therapy for 3 months. After 3 months his PSA was increased to 53. The metastases was spread to spine, ribs and hip bones and lymph nodes.
After that he was scheduled for a radiotherapy treatment of the prostate and surrounding tissues and consequently chemotherapy with Docetaxel (x6). Because of the combined side effects of radiotherapy and chemotherapy, his physical condition was deteriorated dramatically in the first few weeks. He was treated at a Hospital for couple of days in order to improve his general condition. His condition was slowly improved and the side effects were better manageable after 2nd chemo cycle. His PSA was dropped to 0.3 after 6 cycles of Docetaxel.
He spent 6 months without a major health problem after chemotherapy. But then, his PSA increased to 1 after 6 months and jumped to 3.8 in another month. The metastases was spread further to other bones. He has been given Zytiga 4 weeks ago (August 17). Now his PSA is dropped back to 0.5 after using Zytiga (4 pils a day) for a month. He had almost no side effects of Zytiga so far. He will be on Zytiga for another two months initially and will be followed by another PSA check and a screening.