Hi, I am new to this forum. I was diagnosed with aggressive PCA in May, 2013 with a PSA of just below 1700 and a Gleason 8. The cancer had metastasized to my bones. My urologist put me on Zoladex (goserelin) and a bone strengthener Prolia (Denosumab). The effect was immediate and my PSA plummeted to undetectable. When it started to rise, my oncologist placed me on bi-calutamide and once again it went down to undetectable again. When it started to rise for a second time they took me off bi-calutamide and for the third time my PSA dropped. When it started to climb again, my oncologist switched me to Firmagon (degarelix). Although my PSA has gone from 1.3 in July to 2.4 in August (almost doubling) my testosterone level remains undetectable (less than 0.1).
I have appointments in September with my oncologist and two doctors at the Cancer Agency and I am guessing it won't be long before they put me on an androgen receptor inhibitory drug like Xtandi or Zytiga. My question is: "Is there a test to determine if I am susceptible to these drugs, prior to me taking them?"