Statins are sometimes described as being either lipophilic (hydrophobic) or hydrophilic (lipophobic) as though that were a binary condition. While Pravastatin is extremely hydrophilic, fluvastatin is an example of a statin occupying an intermetiate position.
Hydrophilic statins: Pravastatin & Rosuvastatin (Crestor)
Lipophilic: Lovastatin and Simvastatin are the most lipophilic. Atorvastatin & Cerivastatin less so.
I have seen Fluvastatin placed in both categories.
The lipophilic statins tend to increase insulin resistance, which may be a significant issue in PCa, IMO.
"... lipophilic statins diffuse across cellular membranes and exert their metabolic effects in the liver and other tissues; hydrophilic statins require active transport across the cell membrane in order to exert their actions intracellularly. This action of hydrophilic agents is therefore predominantly hepatic and not peripheral" 
Lipophilic statins may be required if the intent is to stop cholesterol synthesis within PCa cells.
 (2012 - U.K.)
"Bone marrow stroma (BMS) was isolated with ethical approval from consenting patients undergoing surgery for non-malignant disease."
"PC-3 binding, invasion and colony formation within BMS was assessed by standardised in vitro co-culture assays in the presence of different statins."
"Statins act directly on PC-3 cells with atorvastatin, mevastatin, simvastatin (1 μℳ) and rosuvastatin (5 μℳ), but not pravastatin, significantly reducing invasion towards BMS by an average of 66.68% ... and significantly reducing both number ... and size ... of colonies formed within BMS."
"Lipophilic statins and rosuvastatin significantly reduced the number of colonies to a similar degree in clonogenic assays and BMS co-culture (Table 1), with simvastatin being the most potent (reduction of 75.44% and 49.44%, respectively)."