Looking for a spot of advice/help/sympathy here....I have Churg Strauss syndrome, which has been successfully kept at bay with methotrexate and plaquenil for about 3 years now. Lately I suffer more and more with dreadful itchiness in my upper arms, mostly in the evenings and during the night, to the point where it can wake me up. Nappy rash cream helps soothe it a bit and after about 2 hours it dies away, but its driving me crazy. I try and distract myself but it is all consuming. Is this a symptom, a reaction to drugs, anybody else had similar???