A GP in my practice is finally listening to my symptoms and not the blood test results. He has given me a trial of 25mg levothyroxine but I really do not feel any better after many weeks. If anything I now have bad hot flushes keeping me awake at night. I wake up with a very bad headache. I am still taking Premarin (lowest dosage) every other day, which the GP said keep taking together with Levo. Obviously I would love to come off Premarin after over 10 years but the hot flushes and other symptoms are awful. I take the Levo with my breakfast as the GP said do not take on an empty stomach. I tried that when I was first prescribed and I felt awful driving to work! Am due at the Dr's tomorrow lunchtime any advice would be greatly appreciated.