levothyroxine & statins : finally had another... - Thyroid UK

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levothyroxine & statins

Wilko91 profile image
9 Replies

finally had another follow up scan for my lung issue . Though not fully recovered, my Atelactasis has reversed/ cleared up. So that is great news. Have lost some weight so BP is improved 132/83. Funnily enough got a call today from my GP surgery ( Gp assistant) about not having been prescribed any statins recently, and told them i am not taking them. Told them it was a hard sell, by the GP at the time to take them, gave my reasons for not having them, and the possible health negatives. Being Hypothyroid etc. This was accepted. Said i would do a Cholesterol test again in about 3 months. I feel i could do with something to help cholesterol on the EPA/ DHA front. As i had done a very recent private test but have seen very little change 6.4 in overall cholesterol levels. ( Didnt mention this in my call today) I may have messed up somewhat, and not helped myself by having my thyroxine, a few hours before i did my blood sample for the test. I need to tweek my diet further, and hopefully get more exercise ( walking) now the weather is improving. I gather omega 3 can help but its which brand and getting the right balance. I believe the EPA levels are the one to focus on. Any thoughts on this Please.

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Wilko91
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SlowDragon profile image
SlowDragonAdministrator

what are your most recent TSH, Ft4 and most important Ft3 results

Plus vitamin D, folate, B12 and ferritin levels

Wilko91 profile image
Wilko91 in reply toSlowDragon

TSH =1.75. T4 =20.5. T3= 4.1. Vit D = 46. Total cholesterol =6.4 . Diabetes HbA1c =38 . All results 2 days ago. Didnt test for a anything else.

SlowDragon profile image
SlowDragonAdministrator in reply toWilko91

Vitamin D is presumably 46nmol as you are in U.K.

how much vitamin D have you been taking daily

Aim to maintain vitamin D at minimum of 80nmol

GP will often only prescribe to bring vitamin D levels to 50nmol.

Some areas will prescribe to bring levels to 75nmol or even 80nmol

leedsformulary.nhs.uk/docs/...

GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)

mm.wirral.nhs.uk/document_u...

But, improving to around 80nmol or 100nmol by self supplementing may be better

pubmed.ncbi.nlm.nih.gov/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly when supplementing

Can test via NHS private testing service

vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function.

There’s a version made that also contains vitamin K2 Mk7.

One spray = 1000iu

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need, with thyroid issues we frequently need higher dose than average

NHS Guidelines on dose vitamin D required

panmerseyapc.nhs.uk/media/2...

Web links about taking important cofactors - magnesium and Vit K2-MK7

Magnesium best taken in the afternoon or evening, but must be four hours away from levothyroxine

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

SlowDragon profile image
SlowDragonAdministrator in reply toWilko91

what’s the range on Ft4 and Ft3

Was test early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

How much levothyroxine are you taking

Do you always get same brand levothyroxine at each prescription

ESSENTIAL to test folate, B12 and ferritin

Test here

monitormyhealth.org.uk/anae...

Wilko91 profile image
Wilko91 in reply toSlowDragon

test was at lunchtime. 100mg taken daily. Brands alternate depending what my local pharmacy has. Generally its Accord. I havent had tested the others tested since 06 /09/24. B12 =327ng/l. Folate =11.2ug/l. Ferritin = 138 ug/l

SlowDragon profile image
SlowDragonAdministrator in reply toWilko91

B12 and Folate were low

Suggest you retest

TSH would be higher at 8-9am

Was last dose Levo 24 hours before test

Wilko91 profile image
Wilko91 in reply toSlowDragon

No i had the Levo a few hours before.

Test result folate and B12
SlowDragon profile image
SlowDragonAdministrator in reply toWilko91

Tested at lunchtime and Levo 5-6 hours before test

TSH =1.75

TSH would have been at least over 2 if tested at 8-9am

Possibly nearer 3

T4 =20.5

Ft4 would have been significantly lower if last dose Levo 24 hours before

Probably below 18 ……possibly lower

T3= 4.1

Need ranges on Ft3

Result below 5.5 is likely low

work on improving low vitamin levels for 2-3 months

Then retest thyroid levels correctly

Suggest you also retest vitamin levels

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

Post all about what time of day to test

healthunlocked.com/thyroidu...

Testing options and includes money off codes for private testing

thyroiduk.org/testing/

Medichecks Thyroid plus BOTH TPO and TG antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes BOTH TPO and TG antibodies, cortisol and vitamins

bluehorizonbloodtests.co.uk...

Medichecks and BH also offer private blood draw at clinic near you, or private nurse to your own home…..for an extra fee

Only do private testing early Monday or Tuesday morning.

Tips on how to do DIY finger prick test

support.medichecks.com/hc/e...

SlowDragon profile image
SlowDragonAdministrator

B12 =327ng/l.

Folate =11.2ug/l

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement

A week later add a separate vitamin B Complex 

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

If Vegetarian or vegan likely to need ongoing separate B12 few times a week

Highly effective B12 drops

natureprovides.com/products...

Or

B12 sublingual lozenges

uk.iherb.com/pr/jarrow-form...

cytoplan.co.uk/shop-by-prod...

In-depth article on different forms of B12

perniciousanemia.org/b12/fo...

B12 range in U.K. is too wide

Interesting that in this research B12 below 400 is considered inadequate

healthunlocked.com/thyroidu...

perniciousanemia.org/b12/le...

And why aiming to keep B12 over 500 recommended

perniciousanemia.org/b12/le...

Great reply by @humanbean on B12 here

healthunlocked.com/thyroidu...

Low folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

healthline.com/nutrition/fo...

B vitamins best taken after breakfast

Igennus B complex popular option. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose and may need 2 per day and/or may need separate methyl folate couple times a week

Post discussing different B complex

healthunlocked.com/thyroidu...

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) Thorne can be difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 3-5 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12 if last test result serum B12 was below 500 or active B12 (private test) under 70

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