Help to interpret first blood results please?… - Thyroid UK

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Help to interpret first blood results please?…

Hyperthyroiddaughter profile image

Hi,

I’ve just collected my daughters blood results (the ones which led to her hyperthyroid diagnosis last week) from her gp after requesting they be printed.

I have no idea how to read them or have any idea what they mean (or which ones are the important ones). Please could someone help this newbie?

Perhaps begin by telling me which ones to list on here? I ‘think’ they show ‘full’ bloods but amongst other things like Liver function, Urea & electrolytes, vit B12, folate etc the only results for thyroid function listed are T4 level and TSH.

Thankyou and apologies for having absolutely no idea what I’m looking at/doing! 🙈

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Hyperthyroiddaughter profile image
Hyperthyroiddaughter
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24 Replies
Buddy195 profile image
Buddy195Administrator

Can you take a photo of the results and attach using the picture icon? If you need to add multiple photos, you need to ‘reply to your own post’ to enable members to see these.

Obviously members here have a wealth of knowledge on thyroid results and key thyroid vitamins, but we also have some members with wider medical knowledge who may be able to comment more widely.

Hyperthyroiddaughter profile image
Hyperthyroiddaughter in reply toBuddy195

Thank you 😊

I’ll try to do that now…

blood test results (pre hyper diagnosis last week)

Blood test results

Sorry, not sure if pic is clear enough.

Thyroid function test:

T4: ‘Above range’ - 19.1 pmol/L [10.3-18.1]

TSH: ‘Below range’ - 0.55mlU/L [0.65-4.41]

Lots of other results listed; Tissue trans, Vit B12, Serum folate, Serum ferritin, Urea & elecrto, Liver function and Plasma C reactive protein.

No others listed on the ‘Thyroid function’ section though.

Really no idea what any of this means!?

SlowDragon profile image
SlowDragonAdministrator in reply toHyperthyroiddaughter

T4: ‘Above range’ - 19.1 pmol/L [10.3-18.1]

TSH: ‘Below range’ - 0.55mlU/L [0.65-4.41]

These do NOT show her to be ‘incredibly overactive’

they show very mildly over range Ft4

incredibly over active result…..would be TSH zero and Ft4 over 30

Results are far more typical of early stage Hashimoto’s - autoimmune HYPOthyroid

Hashimoto’s frequently starts with transient hyperthyroid type results and symptoms before becoming increasingly hypothyroid

We see small but steady number of Hashimoto’s patients initially misdiagnosed with Graves’ disease if antibodies aren’t tested

I would get FULL thyroid and vitamin testing including all thyroid antibodies asap

For full Thyroid evaluation she needs TSH, FT4 and FT3 tested

Very important to test vitamin D

NHS easy postal kit vitamin D test £31 via

vitamindtest.org.uk

test both TPO and TG thyroid antibodies tested at least once to see if hypothyroidism is autoimmune

And test TSI or Trab antibodies for autoimmune HYPERTHYROID - Graves’ disease

Graves Disease antibodies test

medichecks.com/products/tsh...

Low vitamin levels are extremely common especially with autoimmune thyroid disease

About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high TPO and/or high TG thyroid antibodies

Autoimmune thyroid disease with goitre is Hashimoto’s

Autoimmune thyroid disease without goitre is Ord’s thyroiditis.

Both are autoimmune and generally called Hashimoto’s.

Significant minority of Hashimoto’s patients only have high TG antibodies (thyroglobulin)

NHS only tests TG antibodies if TPO are high

20% of autoimmune thyroid patients never have high thyroid antibodies and ultrasound scan of thyroid can get diagnosis

In U.K. medics hardly ever refer to autoimmune thyroid disease as Hashimoto’s (or Ord’s thyroiditis)

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

Post all about what time of day to test

healthunlocked.com/thyroidu...

Testing options and includes money off codes for private testing

thyroiduk.org/testing/

Medichecks Thyroid plus BOTH TPO and TG antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes BOTH TPO and TG antibodies, cortisol and vitamins

bluehorizonbloodtests.co.uk...

Medichecks and BH also offer private blood draw at clinic near you, or private nurse to your own home…..for an extra fee

Only do private testing early Monday or Tuesday morning.

Tips on how to do DIY finger prick test

support.medichecks.com/hc/e...

Hyperthyroiddaughter profile image
Hyperthyroiddaughter in reply toSlowDragon

Wow, that’s ALOT of information and advice there! Thank you so much! 🙏🏼 I can’t take it all in at this time of day I’m afraid, but I will definitely read and digest it thoroughly tomorrow!

However, re your point about the thyroid function results T4 and TSH NOT showing her to be incredibly overactive;

I did speak to a second GP (not the one who initially diagnosed my daughter) and they re looked at her results/notes and said that they actually thought their colleague had gone in too strong re dosage and advised my daughter to drop to 10mg dose per day for first week, then increase to 20mg after a week. Also that the levels weren’t as high as had been made out to my daughter, and not too far above ‘normal’ boundaries!!?

So yes, your comments fit with that!

Buddy195 profile image
Buddy195Administrator

The doctor called her the day after her bloodtest to tell her that they had shown her to be ‘incredibly overactive’ and was prescribing her a daily dose of 30mg of Carbimazole to be followed with bloods again in 4wks and a follow up appointment. He gave her no details of the actual result numbers/ranges.

The above is an extract from your last post.

I’m presuming the test results posted today are your daughter’s second thyroid blood test results. Do you have access to the original test results, as would be useful to compare?

How long has she been taking 30mg Carbimazole?

Hyperthyroiddaughter profile image
Hyperthyroiddaughter in reply toBuddy195

No, these are the first bloods done last week which led to her hyper diagnosis.

Buddy195 profile image
Buddy195Administrator in reply toHyperthyroiddaughter

Thanks for the clarification. I was confused as I did not regard these as ‘incredibly overactive’

I would also upload other sections of the test if you are able. Having key vitamins optimal supports thyroid health.

I’m presuming no thyroid antibody tests were completed? If not, I would definitely push for this as a ‘next step’ (as outlined in your previous post). I say this because I was originally diagnosed as hyperthyroid with Graves BUT thanks to advice from members on this forum, I had antibodies tested and found I am actually hypothyroid with Hashimotos.

Tissue Transglutaminase lgA: 2U/mL [<6.0]

Urea & Electrolytes: Sodium 139mmol/L [133.0- 146.0]

Potassium: 4.4mmol/L [3.5-5.3]

Urea: 2.5mmol/L [3.2-6.4] ‘Outside ref range’

Creatine: 69umol/L [60.0-120.0]

Liver function: Albumin 52g/L [35.0-50.0] ‘Above range’ ‘Outside ref range’.

Alkaline Phosphotase: 85U/L [54.0-143.0]

Alanine aminotransferase: 8U/L [8.0-27.0]

Bilirubin: 16umol/L [3.4-12.0] ‘Above range’ ‘Outside ref range’

Plasma C-protein: <5mg/L [<10.0]

Plasma glucose: 4.4mmol/L [3.6-5.8]

Kidney staging: 0;No AKI

Vitamin B12: 648ng/L [211.0-911.0]

Serum folate: 11.6ug/L; Deficient: 0.35-3.37 ug/L Indeterminate: 3.38-5.38 ugl/L Normal: >5.38 ug/L

Ferritin: 71 ug/L [6.8-75.6]

greygoose profile image
greygoose

Has she started the carbimazole? Because with those results she is going to go very hypo very quickly! And that would not be good.

They do not seem to have tested any antibodies and you cannot diagnose hyper without those. I cannot imagine what is going on in her doctors head but she should be very, very wary of anything he says. He seems to be more than averagely ignorant.

Hyperthyroiddaughter profile image
Hyperthyroiddaughter in reply togreygoose

Hi and Thank you for your reply 🙏🏼

Yes, she has started on Carbimazole and was initially prescribed 30mg per day but had extreme stomach pain after taking first dose, so I phoned GP surgery for advice. I spoke to a different GP who queried why her colleague had given her such a high dose. It was reduced to 10mg per day. She’s now been taking it since Monday. She’s still had lots of stomach pain (today VERY bad this morning) but appart from today, has been much less severe.

I must admit that I’m getting quite confused about it all atm. Could it just be that the Carbimazole is going to take time to start working (as others on here have suggested)? Or has she not been prescribed the right treatment?

Also, forgive me, but I’m not sure what to make of your advice/comments; ‘Has she started the carbimazole? Because with those results she is going to go very hypo very quickly! And that would not be good.’ ??

Should I be scared? Should she stop the Carbimazole? Are you suggesting that she shouldn’t be on it? Or def should be??

Sorry, I’m just completely lost 🤯

SlowDragon profile image
SlowDragonAdministrator in reply toHyperthyroiddaughter

Being hypothyroid will cause poor gut function and low stomach acid

As her test results suggest she’s not hyperthyroid taking Carbimazole will quite likely result in hypothyroid symptoms and results

Suggest you get full antibodies tested AsAP

And see another GP or thyroid specialist endocrinologist

Here’s link for how to request Thyroid U.K.list of private Doctors emailed to you, but within the email a link to download list of recommended thyroid specialist endocrinologists

Ideally choose an endocrinologist to see privately initially and who also does NHS consultations so that might eventually transfer to NHS

thyroiduk.org/contact-us/ge...

Hyperthyroiddaughter profile image
Hyperthyroiddaughter in reply toSlowDragon

Thank you again for all your advice 😊

That’s interesting, if a tad confusing especially because she’s taking Famotidine (to actually reduce stomach acid!) and has been for several months now, before her recent diagnosis of underactive thyroid!

She has more bloods (including antibodies I believe) at very beginning of April.

SlowDragon profile image
SlowDragonAdministrator in reply toHyperthyroiddaughter

That’s interesting, if a tad confusing especially because she’s taking Famotidine (to actually reduce stomach acid!)

Why?

Low stomach acid symptoms very similar to high stomach acid symptoms

Another thing that’s often misdiagnosed

Low stomach acid can be a common hypothyroid issue

Thousands of posts on here about low stomach acid

healthunlocked.com/search/p...

Web links re low stomach acid and reflux and hypothyroidism

nutritionjersey.com/high-or...

stopthethyroidmadness.com/s...

thyroidpharmacist.com/artic...

How to test your stomach acid levels

healthygut.com/articles/3-t...

branchbasics.com/blogs/food...

meraki-nutrition.co.uk/indi...

huffingtonpost.co.uk/laura-...

lispine.com/blog/10-telling...

greygoose profile image
greygoose in reply toHyperthyroiddaughter

Carbimazole is an anti-thyroid drug. It stops the thyroid making thyroid hormone - completely. Her FT4 was only slightly over-range - certainly not hyper! Stopping the thyroid from making any more will cause the FT4 to drop quite rapidly. And we don't even know what her FT3 is!

I think her GP over-reacted due to lack of thyroid knowledge, and she probably is on the wrong treatment - IMHO. But to know if it's the wrong or the right treatment she should have tested the anti-bodies first to get a fuller picture. Until they are tested - or until the next blood test shows her to be very hypo - we cannot know if she should be on it or not. But, speaking personally, I wouldn't have started it until full testing had been done.

It's nothing to be scared of - neither were her original blood test results - they didn't put her in any danger - but it is something to get sorted rapidly because hypo symptoms are no fun.

Yes, I can understand you're lost. It's all a bit complicated at first. But her doctor should have known better and at least have given her a second test in a few weeks time to see if things had changed.

But now I'm confused! Because you say below that she previously had a diagnosis of hypothyroidism. Was she put on thyroid hormone replacement? If she was hypo then she cannot suddenly become hyper, it just doesn't work like that. An underactive thyroid cannot suddenly regenerate and start producing too much hormone. So it all rather sounds like Autoimmune thyroiditis. So, carbimazole would be the wrong treatment, yes.

And being hypo would account for the low stomach acid. The problem is that the symptoms are the same as high stomach acid. So doctors refuse to believe that low stomach acid is a thing, and always prescribe drugs that will lower the acid even further, making things worse. As I said before, doctors know next to nothing about thyroid and we should be very careful about their advice.

She needs her antibodies tested as a priority. If it were me, being as I am, I would probably threaten to sue that doctor if she didn't start doing things correctly, the right tests, etc.

Hyperthyroiddaughter profile image
Hyperthyroiddaughter in reply togreygoose

Once again, Thank you for all of your advice. 😊 I do appreciate it and will certainly take it all onboard.

She is getting antibodies done soon.

However, my daughter has never had a diagnosis of hypo! Only hyper! Maybe I mis-typed that somewhere?? 🙈My apologies if I did!

greygoose profile image
greygoose in reply toHyperthyroiddaughter

OK. It happens. :) Can't find where I saw it, now. No matter, her results are still not high enough to warrant anti-thyroid drugs.

Hyperthyroiddaughter profile image
Hyperthyroiddaughter in reply togreygoose

Yeah, looking back at my posts, I don’t think I did actually but nevermind, it’s fine 😊

Thank you anyway for all your advice. Have a nice wknd.

greygoose profile image
greygoose in reply toHyperthyroiddaughter

You're welcome. :)

pennyannie profile image
pennyannie

Hey there again - I'm guessing you are in information overload -

These blood tests your daughter was diagnosed on show a slightly over range T4 and a slightly under range TSH - and do not, in themselves, shout or even whisper hyperthyroidism.

The antibodies need to be run first, before prescribing any drugs and usually - TPO - TgAB - ABs are run from this first blood sample -

is there any mention there of these abbreviations and with ranges and numbers alongside ?

if with Graves ABs Carbimazole is prescribed - if with Hashimoto's ABs this is not medicated :

Hyperthyroiddaughter profile image
Hyperthyroiddaughter in reply topennyannie

Morning pennyannie ,

Thank you for your reply 😊 Yes, I must admit that I am feeling very overwhelmed! I feel so very grateful for every reply with wonderful afvice that everyone on her posts. 💕🙏🏼 However, I feel a bit like with each one though (and so very new to all of this) I end up going down another rabbit hole and worry. I honestly do feel very lost with it all atm.

I understand what you (and others are saying and even I can see that my daughters results show her to be only just whisper indication of a hyperthyroid. So it certainly makes sense that (as I posted in a previous post) the second doctor that I spoke to,after my daughter began her initially prescribed 30mg dose of Carbimazole, did question why such a high dose and then advised she instead take only 10mgs.

She has done this and has her next (2nd) blood tests in about 3wks time. I believe they will include antibodies which haven’t yet been done.

Am hoping this will give us some more clarity/answers?!

Thank you SO much again 😊

pennyannie profile image
pennyannie in reply toHyperthyroiddaughter

With a patient to patient open forum its inevitable that you get a cross section of forum members trying to help you -

Just stand back. take a breath - and go back to your Profile page -

Just press the Profile Icon sitting on the task bar where you have the Alert Icon -

and read through your posts and all your replies slowly - from the beginning -

Throughout the morning - you'll get some perspective especially with several mugs of a beverage of your choice -

None of us start knowing anything - but stuff does sink in - just allow yourself to breathe and give yourself a break:

Hyperthyroiddaughter profile image
Hyperthyroiddaughter in reply topennyannie

Thank you for your empathy, kindness and advice! 💕

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