Results to interpret please

[Dee8686]

I have been taking 5mcg T3 twice a day. I was originally told to “increase until I feel well” yet that advice has been paused as I had absolutely no benefit from taking the above amount (been on for 4 weeks). Is that just because dose is too low to feel benefit?! I know have to raise slowly. I Haven’t raised yet as trying to sort adrenal issues and a bit unsure where to go from here.

I’m taking all supplements and vitamins are almost optimal. Have been following aip diet and although I feel no different my antibodies have reduced by 300.

Please could someone shed some light on my results? My endo is costing me as fortune each time I speak to him and I can’t afford to keep consulting him. Thyroid hormone resistance was mentioned before and isnperhaps why tsh is high despite high t3.

My fatigue is so bad, I can barely function most days and am having to rest much of the day.

Can anyone suggest what’s going on and where I go to next? My endo hasn’t seen this result yet.

I only take t3. No levothyroxine.

Thank you x

[Dee8686]

Thank you.. yes thyroid hormone resistance was mentioned previously and I was told that the treatment was t3. I am not takig any levothyroxine.

[Dee8686]

Also my endo told me that treatment for this condition is taking t3. I’m so confused

[SmallBlueThing in reply to Dee8686]

With your high thyroglobulin antibody level, the aim may be to suppress any risk of thyroid cancer.

[SmallBlueThing]

With your history of throat infections, have you looked into Epstein-Barr virus?

[Dee8686 in reply to SmallBlueThing]

I have been tested for EBV and test came back negative. I have a gut parasite and an infection though which are currently being addressed with a treatment protocol.

[Dee8686]

Yes I have a thyroid. I stopped takig levo in January and was put on t3 in March. I’m so puzzled too.

Biotin supplements etc were stopped a week prior to the test.

Honestly any advice would be so gratefully received or if anyone can help! I’m so exhausted and finding it very difficult to cope.

[Dee8686]

Well I got sick 9 months after having my daughter so might make sense..

I will thank you x

[greygoose]

You have Hashi's, and with Hashi's, levels can swing around like that. You could not possibly have an FT3 that high on 10 mcg T3 with no levo. Plus your FT4 is quite high, considering you're not taking any. I would say you're at the beginning of a Hashi's flare, and your TSH hasn't caught up with it, yet. Do you have any other labs on 10 mcg T3 only?

[Dee8686 in reply to greygoose]

I don’t have any other lad on t3 only I’m afraid. Every time I have a blood test, nothing is clear as to what I’m to do treatment wise!

[Dee8686]

My last result was pretty similar and before that, my results showed a hashi flare gg

[greygoose in reply to Dee8686]

When was that? And what were you taking at the time?

[Dee8686 in reply to greygoose]

End of feb I had a suppressed tsh of 0.195 and posted on here for explanation (- actually it was you who told me I was having a hashi flare)

I then stopped my levo and waited for next blood test for further instruction.

Next result was 28th March (so I had been on no thyroid hormone at all as instructed by endo)

Tsh 8.68

Free thyroxine 20.1

T4 146

T3 6.53 all same ranges as above.

Was put on t3 only and told I had thyroid hormone resistance. Repeat blood tests needed.

Which brings me to the latest results posted above.

I have been on t3 only at 10mg (5mcg for first 2 weeks) since.

[Angel_of_the_North in reply to Dee8686]

I would be wondering about a TSH-producing tumour as the TSH levels really don't match up with the frees. It could be thyroid hormone resistance but you can tell the difference: "A TSH-secreting pituitary adenoma can be excluded by doing a blood test called ‘alpha subunit’ and a magnetic resonance imagining (MRI) scan of the brain. A test called a thyrotropin-releasing hormone test is also usually carried out to differentiate resistance to thyroid hormone from TSH-secreting pituitary adenoma" Have you had the tests?

[Dee8686 in reply to Angel_of_the_North]

That sounds quite frightening. No, I haven’t... my endo hasn’t mentioned it either. How would I go about getting that?

[Angel_of_the_North in reply to Dee8686]

I think you just suggest it and hope. I was just sent for a load of tests (inc MRI) after an abnormal short synacthen test. I think they are mostly benign (ie not cancerous). My tests were for suspected pituitary adenoma, but I ended up with low cortisol, not high, so they were very disappointed and discharged me. At least then you'd know if it was thyroid hormone resistance.

[Dee8686 in reply to Angel_of_the_North]

I’ve had the short synaxhten test and came back as slight adrenal insufficiency which has been echoed since in my cortisol test which showed 2 lower than average cortisol readings and a high morning cortisol. Thank you I will ask dr x