My latest blood results show that I am in the n... - Thyroid UK

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My latest blood results show that I am in the normal range, so what can I do to reduce my symptoms of low thyroid?

Huffalump profile image
5 Replies

Thanks to all your advice, when I went to the GP's last week for my annual thyroid blood tests, I asked for T3 to be done (which I've never had done before). The nurse asked a doctor who said, 'You can request it, but the lab will refuse.' However, the good news is that they sent me F3 results.

Since I am getting increasing low thyroid symptoms again - pins and needles in my hands, gaining weight despite no change in diet (which is a good diet), fragile skin on my eyelids which are often puffy and swollen, fatigue and brain fog - I was convinced that I was going to discover that my body wasn't converting to F3 - but my results show that I'm in the normal range for TSH, T4 and T3. So where do I go from here to sort my symptoms?

Latest NHS blood results 25th Feb '25 - unfortunately taken at 11.15 am because you don't get any choice of time at my GP surgery - followed your advice about prior levothyroxine timing, fasting, and avoiding supplements in the lead up to it.

Serum TSH - 3.357 mU/L (range= 0.570 to 3.600)

Serum free T4 - 11.0 pmol/L (range= 7.9 to 14.0)

Serum free T3 - 4.5 pmol/L (range = 3.1 to 6.8)

Current Levothyroxine dose - 75mg

Since starting on this forum a fortnight ago and receiving your advice plus doing more research, I am now supplementing with Igennus Vit B tablets, a good Vit D and K2 (previously I did take Vit D in the winter but only when I remembered, which was rarely!). Also Magnesium L-threonate and N-Acetyl Cysteine. (NAC may seem a random choice but it was recommended and seemed to fit with some of my other health issues) I am now avoiding the multivit that I sometimes took because I realised that it contained 50% of the daily recommended amount of iodine. I also make my first meal of the day a homemade green smoothie to get as much good stuff into me as possible and avoid dairy first thing.

Any additional ideas or comments please?

Thanks!

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5 Replies
SlowDragon profile image
SlowDragonAmbassador

Request/politely insist on next increase in Levo to 100mcg

As a ‘trial” I increase if necessary

TSH would have been higher if tested before 9am

TSH should always be below 2 on levothyroxine

gponline.com/endocrinology-...

Graph showing median TSH in healthy population is 1-1.5

web.archive.org/web/2004060...

Guidelines of dose Levo by weight

approx how much do you weigh in kilo

Even if we frequently start on only 50mcg, most people need to increase levothyroxine dose slowly upwards in 25mcg steps (retesting 6-8 weeks after each increase) until eventually on, or somewhere near full replacement dose (typically 1.6mcg levothyroxine per kilo of your weight per day)

cks.nice.org.uk/topics/hypo...

bnf.nice.org.uk/drugs/levot...

nhs.uk/medicines/levothyrox...

Adults usually start with a dose between 50 micrograms and 100 micrograms taken once a day. This may be increased gradually over a few weeks to between 100 micrograms and 200 micrograms taken once a day.

Some people need a bit less than guidelines, some a bit more

Comprehensive list of references for needing LOW TSH on levothyroxine

healthunlocked.com/thyroidu....

onlinelibrary.wiley.com/doi...

If symptoms of hypothyroidism persist despite normalisation of TSH, the dose of levothyroxine can be titrated further to place the TSH in the lower part of the reference range or even slightly below (i.e., TSH: 0.1–2.0 mU/L), but avoiding TSH < 0.1 mU/L. Use of alternate day dosing of different levothyroxine strengths may be needed to achieve this (e.g., 100 mcg for 4 days; 125 mcg for 3 days weekly).

sciencedirect.com/science/a...

The optimal daily dose in overt hypothyroidism is 1·5–1·8 μg per kg of bodyweight, rounded to the nearest 25 μg.

Huffalump profile image
Huffalump in reply toSlowDragon

Thanks - I weigh 62 kilos (sometimes 63) so according to the NICE advice that you linked to, you are right that I should be on around 100mg.

SlowDragon profile image
SlowDragonAmbassador

Retest FULL thyroid and vitamin levels at next test 2-3 months after increasing dose Levo to 100mcg

Which brand of Levo are you taking

is you hypothyroidism autoimmune

Have you had both TPO and TG thyroid antibodies tested

early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

Testing options and includes money off codes for private testing

thyroiduk.org/testing/

Medichecks Thyroid plus BOTH TPO and TG antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes BOTH TPO and TG antibodies, cortisol and vitamins

bluehorizonbloodtests.co.uk...

Medichecks and BH also offer private blood draw at clinic near you, or private nurse to your own home…..for an extra fee

Only do private testing early Monday or Tuesday morning.

Tips on how to do DIY finger prick test

support.medichecks.com/hc/e...

If you normally take levothyroxine at bedtime/in night ...adjust timings as follows prior to blood test

If testing Monday morning, delay Saturday evening dose levothyroxine until Sunday morning. Delay Sunday evening dose levothyroxine until after blood test on Monday morning. Take Monday evening dose levothyroxine as per normal

Monitor My Health (NHS private test service) offer thyroid and vitamin testing, plus cholesterol and HBA1C for £65

(Doesn’t include thyroid antibodies)

monitormyhealth.org.uk/full...

10% off code here

thyroiduk.org/testing/priva...

Huffalump profile image
Huffalump in reply toSlowDragon

The brand they give me changes frequently. At the moment I am on Teva 25 mg and Accord 50 mg. From reading people's experiences on this forum, I now understand that changing brands can sometimes be a problem.

SlowDragon profile image
SlowDragonAmbassador in reply toHuffalump

Yes…..especially Teva

Work out which suits you best then request GP add note on all prescriptions

Either name brand you want or adding note to say “no Teva” if Teva is an issue

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