My private endo has confirmed I am a poor converter and has thankfully prescribed Thybon Henning which should be arriving any day now. I currently take my vitamins with breakfast - B-complex, Vitamin D, VitaminK2 MK7 and take my levo at night with a magnesium spray. My prescription states 5mcg to be taken twice a day. Reading earlier related posts, I note that SlowDragon suggests taking just one dose in the morning for a week or so and then increasing gradually to the full amount, which advice I will follow. My question is this, will I be okay taking the T3 in the morning with breakfast? My other question is, when I start adding the second dose, what would be the best time to do this? My evening meal is usually around 5pm and I eat very little else before bed, maybe a biscuit or a piece of fruit. Thank you as always for your words of wisdom !
Prescribed T3 at long last, advice on when to t... - Thyroid UK
Prescribed T3 at long last, advice on when to take and how to take please
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A quick reply from me.
My prescription states 5mcg to be taken twice a day.
That was my instruction when starting and I would never do that again!
Yes it’s true I was very under-replaced at the time, so lots at play.
But for me, it was way too much, all at once. It actually took me 9 months for constant palpitations to subside, and 6 months after that I’m still figuring out if I need to ultimately take less than 10 a day anyway.
Right now I’m trying out 7.5 a day and although it’s never a straight line, it’s far better than how I felt on 10.
Just my experience.
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Looking at very helpful profile
I reduced my levo from 112/125 mcg to 100/125 mcg and have just retested with MMH
January 2025 results:
TSH 0.42 (0.27-4.2)
FT4 18.6 (12-22) 66%
FT3 4 (3.1-6.8) 24.3%
So hopefully Endo hasn’t suggested reducing Levo?
So Thybon Henning is 20mcg tablet
You will need to cut into 1/4’s to get 5mcg
I would initially start with 2.5mcg (almost a speck of dust) …taking first dose waking ……wait 30-40mins before having anything other than water
2nd 2.5mcg mid afternoon ish - say 4pm
Assuming that’s ok
After 3-4 days increase morning dose to 5mcg
And waiting a few more days before increasing afternoon dose to 5mcg
In few weeks
You can then experiment with taking last dose at bedtime with Levo
Retest after 6-8 weeks with last 5mcg dose T3 at 8-12 hours before test
Aah thank you that's helpful SlowDragon. So 2.5 mcg will be minute, a speck of dust as you say! I would have started with the 5mcg so thank you for clarifying.
Regrettably the endo has stated I should reduce my levo from 100/125 to 75/100. Which is annoying because the GP prescribes 125mcg daily for me. I'm concerned though if I don't follow the instructions from the endo, it will give a misleading result when I retest in 6-8 weeks. My feeling is at the moment to follow what he says, do the test then tweak the levo if I need to. That might of course entail going to the GP and pleading for a reinstatement of a higher levo dose ........
Regrettably the endo has stated I should reduce my levo from 100/125 to 75/100. Which is annoying because the GP prescribes 125mcg daily for me.
Well as you are seeing Endo privately……GP doesn’t need to know about reducing dose
Just continue collecting current prescription
But I guess you might have to reduce levothyroxine as endo requires ….personally I think you have done that already with recent reduction
You can cut Vencamil quite easily
Do you get 25mcg Vencamil too?
Initially only reduce Levo by 12.5mcg for 3-4 days BEFORE starting on 2 x 2.5mcg T3
Then reduce levothyroxine by further 12.5mcg before increasing T3 to 5mcg x 2
You’re are likely to have to increase levothyroxine back up after next test
Yes I get 25mcg of Vencamil so that will make the levo reduction before starting the T3 a little more straight forward. The endo has written to the GP informing them of the proposed reduction. However, I'm hoping I can squeeze my usual prescription in before the GP gets around to changing my prescription. A levo buffer is always welcome to us hypos ! Thank you for your clear guidelines.
Just to quickly add a small thing. If you find it very difficult to split the tablets into 8. Roseway Labs are a compounding pharmacy and reasonably priced. I have 2.5mcg made up by them and it also means you can choose lactose free etc if needed. Best wishes to you.
That sounds a lot less fiddly, thank you for the tip.
You can cut Thybon to 2.5mcg with a semi-decent pill cutter, I did for quite a while. It's not always easy/perfect, but just about doable.