test results : Hi, could anyone shed some light... - Thyroid UK

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test results

Blackberrymoo profile image
16 Replies

Hi, could anyone shed some light on my recent blood tests?

I’ve been off carb for over a month now (have Graves’ disease) all tests in range and also antibodies are non detectable.

I’m still having all different symptoms, fatigue, joint and muscle pain, dizziness, headaches, chest pain, tummy pain.. the list goes on.

I had recent blood tests as though I might be in early menopause (43)

I had these come back, would they be to do with Graves as in coming back or is it a sign of something else going on?

Neutrophil count 7.11 10*9/L [2.0 - 7.0]; Above high reference limit

Erythrocyte sedimentation rate 12 mm/hour

[0.0 - 10.0]; Above high reference limit

Serum ferritin level 155.0 ng/mL [13.0 - 150.0];

Above high reference limit

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16 Replies
SlowDragon profile image
SlowDragonAdministrator

You need full thyroid and vitamin D, folate and B12 levels tested

What were thyroid results BEFORE stopping Carbimazole

what vitamin supplements are you taking

Test thyroid early morning

Monitor My Health (NHS private test service) offer thyroid and vitamin testing, plus cholesterol and HBA1C for £65

(Doesn’t include thyroid antibodies)

monitormyhealth.org.uk/full...

10% off code here

thyroiduk.org/testing/priva...

Blackberrymoo profile image
Blackberrymoo in reply toSlowDragon

Already done, all with in range,

Serum free T4 level 18.2 pmol/L [11.0 - 22.01

Serum TSH level 1.33 miu/L [0.27 - 4.21

B12/folate level

Serum vitamin B12 level 639 pg/mL [191.0 -

663.01

Serum folate level 5.0 ug/L |4.5 - 37.31; <3.0 g/l

Vit D came back as non indicated so don’t know.

Not taking any supplements.

SlowDragon profile image
SlowDragonAdministrator in reply toBlackberrymoo

Folate is very low…..borderline deficient

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help maintain B12 levels

Difference between folate and folic acid

healthline.com/nutrition/fo...

B vitamins best taken after breakfast

Igennus B complex popular option. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose and may need separate methyl folate couple times a week

Post discussing different B complex

healthunlocked.com/thyroidu...

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) Thorne can be difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 5-7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg)

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

helvella.blogspot.com/p/hel...

SlowDragon profile image
SlowDragonAdministrator in reply toBlackberrymoo

Low vitamin D strongly linked to all autoimmune diseases

Recommend you test via NHS private testing service

vitamindtest.org.uk

NHS Guidelines on dose vitamin D required

panmerseyapc.nhs.uk/media/2...

GP will often only prescribe to bring vitamin D levels to 50nmol.

Some areas will prescribe to bring levels to 75nmol or even 80nmol

leedsformulary.nhs.uk/docs/...

GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)

mm.wirral.nhs.uk/document_u...

But improving to at least 80nmol or 100nmol by self supplementing may be better

pubmed.ncbi.nlm.nih.gov/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly when supplementing

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function.

There’s a version made that also contains vitamin K2 Mk7.

One spray = 1000iu

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need, with thyroid issues we frequently need higher dose than average

Vitamin D may prevent Autoimmune disease

newscientist.com/article/23...

Web links about taking important cofactors - magnesium and Vit K2-MK7

Magnesium best taken in the afternoon or evening

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Recipe ideas

bbc.co.uk/food/articles/mag...

Interesting article by Dr Malcolm Kendrick on magnesium

drmalcolmkendrick.org/categ...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

Blackberrymoo profile image
Blackberrymoo in reply toSlowDragon

Thanks for all that, but hasn’t answered my questions regarding the other tests really.

pennyannie profile image
pennyannie in reply toBlackberrymoo

Hey there again :

I think the fact that your TSH has now moved from low / suppressed at 0.01 - to 1.33 - tells me that this first phase of Graves is likely over - and your immune system not now in control of your thyroid.

and this is confirmed as your Graves antibodies were rerun and you state now non detectable -

Generally speaking the NHS allocate around 15-18 months with an AT drug - though recent research suggests longer is better :-

pubmed.ncbi.nlm.nih.gov/338...

How long were you on the Carbimazole ?

The AT drug will take time to leave your body - your TSH and T4 look ' ok ' -

However there it no T3 reading here to put the TSH and T4 into context -

so there is not enough information here to to comment on your thyroid function -

It is one's level of T3 in relation to the TSH and T4 - that causes all the symptoms -

too low a level of T3 for you and you will start having symptoms of hypothyroidism -

just as too high a level of T3 for you and you may well start feeling symptoms of hyperthyroidism :

All things Graves - elaine-moore.com

Blackberrymoo profile image
Blackberrymoo in reply topennyannie

Hi, thank you, I’ve been on it since September last year.

Sorry I thought I put in the T3 as well

Free Tri-lodothyronine (FT3) 5.3 pmol/L [3.1 -

6.8]

I was worried it might be another thing wrong, but I think from all the information I’ve got now, it could just be the graves coming back? Again!!

I have had folic acid supplements from the doctor in the past as my folate levels keep going low but apart from that nothing else.

pennyannie profile image
pennyannie in reply toBlackberrymoo

Ok then - your T3 is coming in at around 59% with your T4 at 65% -

So these are both in their ranges with T3 tracking just behind the T4 which is the right way round - so I doubt these symptoms are Graves -

In fact some of these symptoms are experienced when hypothyroid -

Were you also diagnosed Hashimoto's and had positive TPO antibodies or / TgAB antibodies as well as Graves ?

For some people having one AI disease sees other AI issues develop - such as celiac - gluten intolerance- which might explain the stomach issues - has a test ever been run ?

Just for reference I now aim to maintain my ferritin at around 100 - folate 20 - active B12 125 ( serum B12 500++ ) and vitamin D ar around 125.

 Blackberrymoo I was writing this next bit when you replied.

P.S. A euthyroid ( normal functioning thyroid ) would have a TSH at around 1.20-1.50 with a T4 at around mid point with a T3 running slightly behind the T4 -

so you're not quite there yet - and think you need to give yourself a little more time -

Do you check yourself on pulse, blood pressure and temperature - ideally AM and PM - as these clinical symptoms can help you understand what is happening in your body - and facts to present to your doctor if the blood tests do not well represent how you are feeling ?

So - ok - it seems you also have Hashimoto's and liable to erratic swings in thyroid hormones - sometimes confused with Graves - and why antibodies must be run - and which is not medicated with an AT drug as the T3 and T4 fall back down into range by themselves - but ultimately the thyroid becomes damaged and the patient becomes hypothyroid and eventually prescribed thyroid hormone replacement/

All things Hashimoto's - many forum members follow the research and suggestions of Dr Izabella Wentz who writes s thyroidpharmacist.com

Blackberrymoo profile image
Blackberrymoo in reply topennyannie

Ohh yes! I tested positive for both TPO and and TRAbs but was never told I have both just graves.

TSH receptor antibody level 1.13 u/L 10.0 - 0.41;

Serum thyroid peroxidase antibody

concentration 47 iu/mL [0.0 - 33.01;

I had a celiac test done over 10 years ago which was negative.

pennyannie profile image
pennyannie in reply toBlackberrymoo

I've added on a reply up in my last post that I was editing when you pinged me :

So it is quite common when the immune system attacks the thyroid thyroid that there is a ' grey area ' and several different antibodies are found positive -

Graves Disease is said to be life threatening if not medicated - so takes precedence and the treatment is with an AT drug - which ' just buys you time ' while we wait for your immune system to calm back down again and hopefully the thyroid reset itself without the need for any drugs.

There is no medication for Hashimoto's - the T3 and T4 do not rise higher and higher as in Graves but fall back down into range without any medical intervention - but with successive immune system attacks and thyroid gland becomes increasing disabled and thyroid hormone production reduced and the patient becomes hypothyroid -

Stomach, gut and bowel issues are common with Hashimoto's and many need to consider checking intolerance to food stuffs with the usual suspects being gluten, dairy and wheat.

Blackberrymoo profile image
Blackberrymoo in reply topennyannie

Ok, thank you for all your replies it really has helped. 😊 I have to have my thyroid levels checked again in 3 weeks to see how they are doing, so if they are starting to look like they are going the other way does this mean it’s going to be Hashimoto from now on?

pennyannie profile image
pennyannie in reply toBlackberrymoo

I would think so - as these results do not look like active Graves -

and it could be that the AT drug is still having some bearing on your blood test results -

the AT drug has been controlling your metabolism for over a year - and you only stopped treatment a month ago.

I detailed above ' euthyroid ' TSH, T3 and T4 blood test levels - they are just ball parks - as having been diagnosed Graves and / or Hashimoto's I question if we ever fall back into what is considered ' normal ' levels by some medical professionals.

pennyannie profile image
pennyannie in reply toBlackberrymoo

If you want - throw them up on here on the forum - if looking for reassurance - alongside these results and we should be able to see some changes and hopefully some relief in these symptoms being tolerated.

Blackberrymoo profile image
Blackberrymoo in reply topennyannie

Thank you, I will definitely do that 😊 x

SlowDragon profile image
SlowDragonAdministrator

Only very slightly high ESR

ncbi.nlm.nih.gov/books/NBK5....

Ferritin only very slightly raised

Ferritin is often high with Graves’ disease.

Neutrophil count only slightly high

patientpower.info/what-do-h...

Blackberrymoo profile image
Blackberrymoo in reply toSlowDragon

Thank you, that’s what I needed to read.

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