Should I push for an ultrasound of my thyroid? ... - Thyroid UK

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Should I push for an ultrasound of my thyroid? I have primary hypothyroidism without Hashimoto's...

melissa-b profile image
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Hi guys, I'm back! 4 months ago I asked to go up on my dosage of levothyroxine (I was on 50mcg) but the GP declined. However, I had a blood test again yesterday and my TSH has gone up more, and my T4 dropped more, so they are letting me go onto 75mcg - result! As of the last blood test (yesterday), my TSH is 6.73mIU/L (range 0.38-5.33) and my T4 is 12.4pmol/L (range 8-18.0). I'm going to start the 75mcg tomorrow. My other vitamins and minerals are looking good, and I'm still taking supplements, but my potassium was a bit on the low side (3.5mmol/L with a range 3.5-5.3).

However, I've been taking Mercury pharma 25mcg twice a day - I tried another brand of 50mcg (I can't remember which one!) and broke out in an itchy rash all over my body, so had to take two 25mcg Mercury ones instead. I don't know if I should take three Mercury pharma tablets or get the new 75mcg ones the GP has sent to the pharmacy, as I don't want to get a rash again but taking three tablets is a bit annoying as I also have some joint issues - do people who have taken Mercury get on well with any other brands?

Additionally - lately, I've been having even more symptoms of hypothyroidism (not surprising seeing my TSH getting higher and higher) - extreme fatigue, joint pain, thinning eyebrows, weight gain, high blood pressure (diastolic), but also a hoarse voice and pressure on and around my throat. This pressure is worse when I'm lying down flat on my back. It's been getting worse over the past 6 months or so. Should I ask my GP for a referral for an ultrasound on my thyroid? I don't think I have a goitre or anything. I tested negative for Hashimoto's so I'm not sure why my thyroid is failing. Thank you!

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8 Replies
FancyPants54 profile image
FancyPants54

There's more than one antibody to test but the NHS usually one do one of them unless you push for both. You can be negative in one and positive in another thus Hashimoto's can be the cause. Some never have antibodies show up on tests but it can still be hashimotos.

I am not surprised you have symptoms. Being kept on a 50mcg starter dose is ridiculous. And now your blood test has proved it. We should be aiming for a TSH around 1 or below. Trouble is our doctors often don't agree.

I can't remember which manufacturer produces 75mcg tablets. There's only one I think. It might be Teva. I would ring the surgery back and request to have your increase provided by a 25mcg tablet and a 50 tablet. Then you could have both from Mercury.

melissa-b profile image
melissa-b in reply to FancyPants54

Thank you for your comment! I had private tests which had Thyroglobulin Antibodies and Thyroid Peroxidase Antibodies that were negative (as well as negative ANA and CRP), a couple of times, so I'm guessing it isn't Hashimoto's - but I wondered if anything structurally could be going on with the pressure on my throat! I agree - I'm hoping to get my TSH to 1 or under, it's never been close! I'll ask my pharmacist about that and find out - I didn't know Mercury did 50mcg tablets, either!

FancyPants54 profile image
FancyPants54 in reply to melissa-b

Most brands do 50's. It's the 75's that are limited. Probably because most people are only transitioning at the 75mcg point, likely to end up on higher so it's no worth the manufacturers producing the tablet.

You can ask for a scan. I have had one. But I got told off when I turned up for it as the person who was doing it said I was taking up a space and it wasn't necessary. My thyroid has shrunk because I've been taking medication for years. But I felt so small being told off for wasting his time like that.

melissa-b profile image
melissa-b in reply to FancyPants54

I'm so sorry to hear about your experience, that sounds dreadful <3 I'm a bit concerned about the same thing ☹️

helvella profile image
helvellaAdministratorThyroid UK in reply to melissa-b

helvella - Thyroid Hormone Medicines - UK

The UK document contains up-to-date versions of the Summary Matrixes for levothyroxine tablets, oral solutions and also liothyronine available in the UK. Includes injectables and descriptions of tablet markings which allow identification. Latest updates include all declared ingredients for all UK products and links to Patient Information Leaflets, etc. PLUS how to write prescriptions in Appendix F.

dropbox.com/s/bo2jzxucgp9hl...

Screenshot of levothyroxine matrix
melissa-b profile image
melissa-b in reply to helvella

Thank you for this doc! Looks like Mercury does 50 and 75, I don't know why they're making me take 25mcg 😆 And i found from my notes, it was Accord that made me extremely itchy, so at least I can avoid that. I also saw that in New Zealand (I think), Mercury Pharma isn't being used (for new patients) as it didn't show it had bioequivalence... Interesting

EDIT - I read the wrong part of the document, Mercury is indeed only available as 25mcg tablets!

helvella profile image
helvellaAdministratorThyroid UK in reply to melissa-b

No! Mercury do 25, 50 and 100.

There are a few countries in which it is accepted that not all makes are equivalent.

melissa-b profile image
melissa-b in reply to helvella

Oh how strange, I'll speak to the pharmacist about that then! Although I would prefer to take just one 75mcg tablet - do you recommend one make above another? Or should I look at the fillers in Accord and make sure whatever I take doesn't have the same ones? Thank you :)

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