Due to fact I need to start something for my bone health, I have come across that melatonin along w/3other supplements shows great promise in resorption and building of bone. However, I have read that melatonin may interfere w/TSH levels. Then, an abstract from endo publication showed that exogenous melatonin (15mg) showed marked decrease in removing anxiety & depression. Any posters have long term experience w/melatonin?
melatonin & hashi's: Due to fact I need to start... - Thyroid UK
melatonin & hashi's
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15mg of melatonin is quite a high dose. I'm prescribed 3mg which works to help my sleep disorder.
I have no knowledge of anything else it helps other than sleep and not noticed it affecting TSH.
I’ve taken 5mg at night for years. This helps my sleep. I have suppressed TSH because I take NDT but this hasn’t changed for years
15mg is a massive dose. Doses of 3 to 5mg or lower are the norm. I would not be over concerned with one publication reporting an effect of very high dosing.
Would you copy the link to the bone health and supplements you mention?
endocrine-abstracts.org/ea/...
drmasiello.com/2017-06-stro...
connect.mayoclinic.org/disc....
There is a strontium ranelate allowed in UK as last chance, not rx here in US -scary side effects. I have a couple more bookmarked, but won't bog you down!
Terebol, have you noticed any effect on your liver from taking this higher dose of melatonin? I've read some studies that it can reduce inflammation, which interests me because when my TSH is high, so are my liver enzymes, particularly Gamma. When TSH is normal, the liver tests come back in normal range. Of course the liver also has a key role in metabolizing any kind of medicine.
I take 1mg melatonin and it's more than enough, I feel sluggish the next morning. I only take it when I really need to sleep, for example during this terribly hot summer.
That is interesting - the liver effect. I am not, currently, taking melatonin as it has never helped me sleep. I will be discussing this w/my endo as alternative to rx bone meds. Read my response to jgoodwin977 re tulsi tea. What works for one, may not work for another, but good to have input.
I just ordered 10mg coz my insomnia is so bad and was told it’s also good for cancer. After reading the comments, maybe I’ll stick to 5mg, although I still don’t sleep with that, maybe it’s my adhd. I’ve got my tsh down, so when you say interferes, do you mean it makes the tsh go up in numbers or down? Thanks
Melatonin was never dependable for helping me sleep. My interest is in its part in bone health. What I have found helpful for my anxiety/overactive mind @2:30am has been tulsi tea. It has more grams of the tulsi blends than taking the capsules. Being summertime, I make a concentrated tusi tea & dilute. It was, particularly, interesting of the anxiety/depression reduction.
I am following this post with interest. I would be interested in reading the article about bone health. I’ve been trying to find info about melatonin depleting b vitamins. I heard one person mention this in a conversation but have never found any data supporting that statement….