inflammation in my body: I am on thyroxine and T... - Thyroid UK

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inflammation in my body

elwins profile image
48 Replies

I am on thyroxine and T3 have developed inflammation in my body, have had T3 and Tsh tested recently. Could thyroid antibodies be causing my problems. Have been on thyroxine for over 70 years. Latest results

TSH 0.03 mu/L range 0.35-4.9

Serum free triodothyroxine level 3.09 pmolL range 2.4 -6.0

I am under a well known thyroid specialist. Seeing him by zoom privately.

Who has requested various tests which my doctor’s have done on the NHS.

taking half a tablet T3 each day split into 2 doses. Then 50 thyroxine a day

Trying to find out what is causing my raised ESR levels

Symptoms of extreme fatigue, thinning hair, and achy body.

Any advice would be welcome

Thanks

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elwins
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48 Replies
Jaydee1507 profile image
Jaydee1507Administrator

50mcgs Levo a day is a low dose in combi therapy.

Do you have an FT4 result as well with these results?

How did you take the test? Time of day? Last dose of Levo & T3 were taken how long before the test?

What are you supplementing with?

What are your latest results for ferritin, folate, B12 & D3?

elwins profile image
elwins in reply toJaydee1507

Had tests done as advised on this site.

Vit d 80 nmol/ range 50-200

B12 366 ng/L range 187-883

Folate 12.3 ug/L range 3.1-20

ferritin done 26 March 171 ug/L range 30-332

Everything else done 17 May

only free T4 13.6 pmol/L range 9.1-17.6

Jaydee1507 profile image
Jaydee1507Administrator in reply toelwins

Its more likely that low thyroid hormone levels are causing your symptoms than antibodies.

Your FT4 is only 53% of range and needs to be much higher.

Are you taking any supplements - which ones?

Your B12 level is quite low so you wont be able to convert well and use your thyroid hormone well.

Are you vegan or vegetarian? If not:

B12 - do you have symptoms of B12 deficiency? The reference range for B12 is very wide and cut off point too low. theb12society.com/signs-and...

If you do then you should discuss this with your doctor for further tests for Pernicious Anaemia.

If not, then start with a methyl B12 sublingual spray or lozenge for a week, then add a good B complex. Once you run out of the separate B12 just continue with the B complex.

cytoplan.co.uk/vitamin-b12-...

amazon.co.uk/Better-You-Boo...

B complex suggestions: Slightly cheaper options with inactive B6:

amazon.co.uk/Liposomal-Soft...

Contains B6 as P5P an active form:

bigvits.co.uk/thorne-resear...

healf.com/products/basic-b-...

Explanation about the different forms of B6:

helvella.blogspot.com/p/hel...

B complex comparison spreadsheet:

healthunlocked.com/thyroidu...

You may yet benefit from adding a small amoutn of T3 but need to get your FT4 higher first to see if its still required.

elwins profile image
elwins in reply toJaydee1507

Only gluten free, not vegan or vegetarian. Take vitamin d and vitamin b12 use better you spray. Thanks for advice.

Jaydee1507 profile image
Jaydee1507Administrator in reply toelwins

Recommend aadding in a good B complex, some suggestions above.

Pinkisland profile image
Pinkisland in reply toJaydee1507

Hi Jaydee, please can you explain the difference between inactive B6 and B6 as P5P an active form. I would like to take a B complex without B6 if there is one, as I suffer from neuropathy. Many thanks

Jaydee1507 profile image
Jaydee1507Administrator in reply toPinkisland

This link will explain the difference between the 2 forms of B6:

helvella.blogspot.com/p/hel...

If you buy the P-5-P form in a low dose you should be fine.

Pinkisland profile image
Pinkisland in reply toJaydee1507

Can you please recommend a B complex which is in the P-5-P form.

Jaydee1507 profile image
Jaydee1507Administrator in reply toPinkisland

There are 2 on the list above. Thorne Basic B is one.

Pinkisland profile image
Pinkisland in reply toJaydee1507

Thank you

FW23 profile image
FW23 in reply toPinkisland

Hi Pinkisland hope you don't mind me asking an off shoot question? I have neuropathy which I can't get rid of. Is there a conection with B6. Thanks

Pinkisland profile image
Pinkisland in reply toFW23

I believe there might be from my limited knowledge and reading but I'm no expert. That is why I am trying to find a B complex with the right kind and amount of B6.

FW23 profile image
FW23 in reply toPinkisland

Thsnk you.

Kmollls profile image
Kmollls in reply toJaydee1507

I’m so glad I found this site bc you are so helpful!

greygoose profile image
greygoose

Your FT3 is very low:

FT3: 3.09 pmol/l (Range 2.4 - 6) 19.17%

Not surprising you have hypo symptoms like fatigue and hair-loss. And that could very well be what's causing your inflammation.

elwins profile image
elwins in reply togreygoose

Thanks much appreciated. Started taking T3 after blood test done on advice of Professor. Cannot mention name due to guidelines.

greygoose profile image
greygoose in reply toelwins

no, no, I wouldn't expect you to. But you do need an increase in your dose of T3. It's much too low for good health.

Kimkat profile image
Kimkat in reply togreygoose

I’m on the same dose but it’s because I have a pacemaker so he’s starting off low with a possibility of increasing gradually

greygoose profile image
greygoose in reply toKimkat

That's the way it should be done with or without a pacemaker. But it can be too gradual, which is not good either. How long have you been on your present dose,

Kimkat profile image
Kimkat in reply togreygoose

I only started it on Sunday, my gp practice still haven’t made up their minds whether I should be given it on prescription or not, so while they’re deliberating I ordered some through the private endocrinologist 🙂

greygoose profile image
greygoose in reply toKimkat

Ah, ok, so that blood test was done before you started it! That explains it. lol So, it's too early to tell anything. But pretty sure it's that low FT3 that is causing the symptoms. :)

Kimkat profile image
Kimkat in reply togreygoose

yes I have another appointment in 6 weeks time to see how I’m getting on

greygoose profile image
greygoose in reply toKimkat

Right. So how much T3 are you taking? Waiting six weeks is a bit excessive. If you started on 5 mcg, in theory you could increase that by 5 mcg in two weeks time.

Kimkat profile image
Kimkat in reply togreygoose

It’s actually 5 weeks I wrongly calculated that. I take 10 mcg a day at the moment split into 2 doses . The endos secretary did say she would contact me in a couple of weeks to see how I’m getting on.

greygoose profile image
greygoose in reply toKimkat

ok well that's actually rather a high starting dose. We normally advise starting on 5 mcg.

Kimkat profile image
Kimkat in reply togreygoose

Is that 5 mcg once a day?

greygoose profile image
greygoose in reply toKimkat

yes

Kimkat profile image
Kimkat in reply togreygoose

Oh ok, the Prof I am seeing said that I needed 5 twice a day so I went with that. I feel ok at the mo, not sure when it will kick in

greygoose profile image
greygoose in reply toKimkat

You may very well need that, but it could be too high to start on - especially as he said he was starting you low due to your pace maker! I thought you were going to say 2.5 mcg! lol So, be aware he doesn't know much about dosing. Any future increases should be no more than 5 mcg.

Kimkat profile image
Kimkat in reply togreygoose

I have emailed his secretary, just in case but he did say to split my tablets into quarters ( they are 20mg) and take one quarter in the morning with my Levo and another quarter in the afternoon

greygoose profile image
greygoose in reply toKimkat

Yes, I'm sure he did. But that doesn't make him right.

If you're ok on that dose, that's fine. But just be aware that in the future, he might want to increase by too much because he doesn't really understand what he's dealing with.

Kimkat profile image
Kimkat in reply togreygoose

He did say that I may be good on that dose and that I may not need an increase, only the blood tests will determine that, I suppose it’s all trial and error but fingers crossed. I haven’t had any palpitations yet anyway 🤞🏼

greygoose profile image
greygoose in reply toKimkat

It should be how you feel that determines that. But, you do realise that your TSH is going to be very low on 10 mcg T3. I hope he understands that.

Kimkat profile image
Kimkat in reply togreygoose

I hope he understands that too, he’s not cheap 😄 I’ll see what his secretary comes back with after my email.

Kimkat profile image
Kimkat in reply togreygoose

This is my latest blood tests from June

Blood tests
greygoose profile image
greygoose in reply toKimkat

So, that was before you started the T3. Well, you obviously needed it. You're a very poor converter according to those results.

But, did you leave a gap of 24 hours between your last dose of levo and the blood draw?

Kimkat profile image
Kimkat in reply togreygoose

Always 🙂

greygoose profile image
greygoose in reply toKimkat

Good. :)

sparkly profile image
sparkly

My crp has been raised for years and not one gp or consultant bats an eye and just change conversation when I bring it up. It is something to keep an eye on but likely you never find out what causes it.I'm hoping mine will finally be in normal range as I've hopefully reversed my fatty liver and high/ low cholesterols and likely insulin resistance.

I know crp was very high when liver ALT's were sky high so that definitely plays apart in it for me

radd profile image
radd

elwins,

All antibodies create inflammation.

Usually good and necessary that help deal with and heal cuts, infections, colds, etc. Once resolution is found the inflammation reduces. This is a healthy immune response.

Auto-antibodies created by attacks on self healthy tissue are not a healthy response and these antibody type can linger for many years creating chronic inflammation. Chronic inflammation causes further damage, invites other conditions and becomes self driving.

This is why many members advocate to reduce their thyroid antibodies, so reducing unwanted and damaging inflammation.

Otto11 profile image
Otto11

Hi have I missed it but you didn’t say what your ESR level is.

Puddingym profile image
Puddingym

sorry to hear about your aches. I was quite similar, frizzy hair, aching was horrible, tired and skin gone to pot. All my levels were fine apart from my TSH, I saw a NHS doctor and he said the TSH will always be high as I have an autoimmune disease. It will never come down. All that aside I started taking wild yam cream from Napiers of Edinburgh and the aches almost went immediately, it’s amazing, look into it and let me know what you think, worth a try. If you don’t mind, Could you let me have your private thyroid consultants No, I could do with seeing one, as I would like to get clarification on my TSH. Thanks.

elwins profile image
elwins in reply toPuddingym

Replied to you personally following correct guidelines of the site.

elwins profile image
elwins

thanks everyone for your advice my ESR level is 50 mm/h range 1.0-20.0.

Brightness14 profile image
Brightness14

i have no thyroid and have experienced the same symptoms as you especially inflammation when my FT3 is too low yours is low . Also 50 Levo is small to.

elwins profile image
elwins

thanks for that.

Dahli profile image
Dahli

Hi. Please can I just check some of your symptoms, is any of the discomfort involving shoulder joints, knees or ankles & on both sides? Gill

elwins profile image
elwins in reply toDahli

On both sides ankles and feet plus I have ave problems with lower back.

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