test interpretation help please

[Polarbear54321]

help with test result interpretation please.

retest using monitor my health as I though NHS test might have been affected by taking a multi vit (which I stopped a week before this test). Was overactive and gradually put on 75 levothyroxine. Should I be reducing this amount as now over active? My TPOs have also gone up from 215 to 233.

TRIODOTHYRONINE

27/02/2024

5.4 pmol/L

FT3 levels normal (normal range 3.1 - 6.8 pmol/L)

THYROXINE

27/02/2024

22.8 pmol/L

FT4 levels high (normal range 12 - 22 pmol/L)

THYROID STIMULATING HORMONE

27/02/2024

0.1 mu/L

TSH levels low (normal range 0.27 - 4.2 mU/L)

previous results below

TRIODOTHYRONINE

02/10/2023

4.6 pmol/L

FT3 levels normal (normal range 3.1 - 6.8 pmol/L)

THYROXINE

02/10/2023

15.1 pmol/L

FT4 levels normal (normal range 12 - 22 pmol/L)

THYROID STIMULATING HORMONE

02/10/2023

5.61 mu/L

TSH levels high (normal range 0.27 - 4.2 mU/L)

[SlowDragon Administrator]

was test early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

how long have you been on 75mcg

Do you always get same brand of levothyroxine

Have you tested vitamin D, folate, ferritin and B12

What vitamin supplements are you taking

If you feel over medicated you might want to reduce dose levo a little

Eg 62.5mcg 3 days and 75mcg 4 days

[Polarbear54321 in reply to SlowDragon]

Followed all instructions on here re test.

Vits I am still taking zinc (which I was low on) and vit d. I was tested for all vitamins by nhs when diagnosed (so October). I can’t afford to be testing all the time.

I have the same brands but the 50 tablet is a different brand to the 25 tablet. I have been on 75 for 12 weeks

[Sleepman]

Hi Polarbear.

I am pretty new, doesn't it take time to get your head around all the stuff.

I am about a year further on and I am trying to optimise my vits and minerals now. Been on B complex and vit D spray for about a year but not got enough blood data to know if levels are OK. Then I stopped B complex (Biotin) as I was trying to retest bloods then got a bit out of the habit with Christmas etc, ---- uuuughg. I am generally OK.

Rounding off you are 60% T3 and 100% on T4 -TSH 0.1 It is one test though.

So multi vit did not change (Biotin ) your TSH result much.

How do you feel on this dose ? It is early days on your thyroid hormone and things will be moving about and settling. If you feel wellish, I would stay as you are for a bit.

Read about overactive symptoms on TUK website etc and keep an eye for them.

I think your body will still be in repair and settling in mode ? Levels might still be moving about ?

Would welcome others more knowledgeable to chip in.

Doctors are supposed to medicate based on symptoms not just the numbers.

[Polarbear54321 in reply to Sleepman]

Doesn’t seem like the multi vit has made any difference to my blood tests no. It’s very confusing. I have generally been feeling much better since starting levo. I have had a few weird symptoms this week like nervous feeling in tummy and not being able to focus at work, but then it has been a stressful week. The symptoms aren’t consistent though and come and go. I also fell asleep randomly on the sofa on Monday 4pm which is more of a hypo than hyper symptom 🤷‍♀️

[Sleepman]

Glad you are generally OK. Sounds like you are in optimising phase. Your T3 numbers look encouraging that you convert T4 reasonable well.

I have patches when still fall asleep late afternoon still.

I cannot take gluten and that seems to feed the hypo fatigue symptoms. I was clear on celiac test but it seems gluten feeds the antibodies that attacked my thyroid.

I was off gluten nearly a year before autoimmune UAT diagnosed.

Resting Blood pressure and pulse might be worth monitoring just so you know where you normally run and can see any changes ?

[greygoose]

You have Hashi's/hypo, so you cannot become hyper, however, results can fluctuate a lot with Hashi's. That's the way it works.

That said, your FT3 is not at all high, it's just your FT4 very slightly over-range. So, if you feel ok with those levels, then don't change anything. But, if you should start to feel a little hyper, just reduce your levo slightly by yourself - do not involve your doctor because they just do not understand Hashi's fluctuations. And if they reduce a dose, they are very reluctant to put it up again!

Doesn't matter about the antibody levels. Once you have had a positive result and know that you have Hashi's, there is no point in retesting. Antibodies fluctuate all the time so the actual levels don't mean anything.