Please note I have not had a Thyroid diagnosis and am not on any meds. As part of a well woman check I had thyroid blood tests. Results are as follows-
TSH-1.72 mlU/L (0.35-5.5)
FT4-17.9 pmol/l (11.9-21.6)
FT3-4.92 pmol/l (3.1-6.8)
Anti-Tg-115.0)
Anti-TPO-34.0)
TBG-24.5ug/ml (6.3-22.7)
The only one flagged is the last one-TBG. The notes said that although this was high, it didnt mean anything as the other results were fine and I dont fall into the other categories mentioned ie Im not pregnant or on HRT, so what does it actually do? Thanks for any info 🙂
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ValDee88
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TBG is thyroxine binding globulin. It binds with the thyroid hormones (T3 and T4) and transports them in the bloodstream. Its used to aid diagnosis of thyroid conditions when FT3 (free T3) and FT4 (free T4) are not within the normal range. The FT3 and FT4 are the important numbers as far as thyroid issues go. I think there are a few reasons why TBG can be raised, but you are only a little over range, and as long as you feel well I wouldn't worry about it. NB: I'm not a doctor!
With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement
A week later add a separate vitamin B Complex
Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.
If Vegetarian or vegan likely to need ongoing separate B12 few times a week
IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results
In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12
Post discussing how biotin can affect test results
I have a lot of symptoms so Ive just had a well woman check, which contained a thyroid panel. I suspect a lot of my issues stem from long term low/deficient B12, D and folate. Thank you so much for all of this info, it is incredibly helpful 👍
Retest thyroid and vitamin levels in say 3-4 months
Ferritin might be better nearer 100
Look at increasing iron rich foods in diet
Eating iron rich foods like liver or liver pate once a week plus other red meat, pumpkin seeds and dark chocolate, plus daily orange juice or other vitamin C rich drink can help improve iron absorption
I am not familiar with how to interpret thyroxine binding globulin. It hardly ever comes up, and I'm a bit surprised it was included in a well woman check up. I've never had it tested (just checked my records), and have had serious thyroid issues for over a decade.
I just wanted to mention that your thyroid panel blood tests (TSH, freeT4 and freeT3) all look excellent. It is quite interesting to see a healthy set of results, as we usually see results from failing thyroids.
TSH stands for thyroid stimulating hormone, it is a hormone that increases when the body needs more thyroid hormone, to call on the thyroid to make more. A healthy number is around about 1-1.7 . Both freeT4 and freeT3 are measures of how much hormone is available in your blood. For both of these the range given is a normal curve, which means most healthy people will have results near the middle of the range. The closer to the extreme ends of the range you are the less likely you are to have a healthy thyroid. Yours both look nice and close to the centre.
These results show that at the moment your thyroid is performing great, and doing what you need it to do.
Just a noted for anyone besides the original poster who might be reading. These results are great for a healthy thyroid on no medication. But once you are ill and taking thyroid hormone replacement, ideal results are quite different. Replacement hormone does not work in the same way as natural hormone produced by our own thyroid gland.
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High thyroid globulin with normal TSH
Reducing dose of thyroxine 
No thyroxine 
Getting an Endo Referral - Thyroxine levels not right?
high free thyroxine and normal tsh.. difficulty to conceive
