How to reduce high antibodies : hi I am... - Thyroid UK

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How to reduce high antibodies

Petrahorse profile image
8 Replies

hi

I am Hashimotos diagnosed 2021. Have attached latest blood test with ranges. Can anyone help me to reduce my antibodies which just keep rising with each blood test? I am gluten free, take 50mcg Levo daily first thing, magnesium, vit B complex, k2, and selenium. Feeling really tired everyday for most of the day but especially from around 4pm, any stress sends my tiredness through the roof, however small ☹️ Constant headaches (normal for me), burning eyes and lots of muscle aches. Due to see a new Endocrinologist in December.

Thank you.

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Petrahorse
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8 Replies
Jaydee1507 profile image
Jaydee1507Administrator

You're clearly not on the right dose of thyroid hormone. 50mcgs Levo is just a starter dose although its strange it is suppressing your TSH.

Have you taken T3 before or been hyper at some point?

Free T4 (fT4) 17.5 pmol/L (12 - 22) 55.0%

Free T3 (fT3) 4.8 pmol/L (3.1 - 6.8) 45.9%

You are converting well but your FT4 is on the low side for Levo only therapy. You clearly need a dose increase.

Have you tested your vitamins lately? What were the results?

Reducing antibodies isnt going to help much at all as they don't cause symptoms in themselves. Better to address your thyroid hormone needs.

It's ideal if you can always get the same brand of levo at every prescription. You can do this by getting GP to write the brand you prefer in the first line of the prescription. Many people find that different brands are not interchangeable.

Petrahorse profile image
Petrahorse in reply toJaydee1507

Thank you. I have on occasions increased my Levo to 100mcg and felt better. Never taken thyroid hormone meds. Will look at vitamin test too

Also taking estrodial and utrogestan as I’m 54 and menopausal.

greygoose profile image
greygoose in reply toPetrahorse

Levo is 'thyroid hormone meds'. It's the thyroid hormone T4. :)

As Jaydee says, it's not the antibodies that are causing your symptoms. They are the result of your thyroid problem, not the cause of it. Which is why they are used as a marker to see if you have autoimmune thyroid problems.

With Hashi's, your immune system, for some reason, mistakes the thyroid for the enemy and sets about destroying it. With each attack, a certain number of cells die, releasing their contents into the blood stream. Their contents include: T4, T3, thyroglobulin and thyroid peroxidase. The T4 and T3 are used up or excreted. But the Tg and TPO need to be got rid of, because they shouldn't be in the blood. So, that's where the antibodies come in, to clean up the blood. So, lowering them wouldn't help your symptoms - they are due to your low FT3 - and might not be a good idea given that they do have a job to do. :)

Petrahorse profile image
Petrahorse in reply togreygoose

Thank you. All these time I thought I needed to get my antibodies down or they would continue to destroy my thyroid and eventually leave me with no functioning thyroid at all. I can see they are cleaning up the blood as you say.

greygoose profile image
greygoose in reply toPetrahorse

Yes, it's not the TPO/Tg antibodies destroying the thyroid. it's the lymphocytes produced by your immune system. And there's nothing you can do to reduce them. The disease has to run its course, I'm afraid.

DippyDame profile image
DippyDame

I'd be concerned about your thyroid hormones rather than your thyroid antibodies...the former are too low

However many with Hashi's get relief from a gluten free diet, as you are following.

50mcg levo is is not sufficiently raising your FT4 which should convert to T3 so raising your FT3....your T4 to T3 conversion is thankfully fine

Both Frees need to be approaching 75% through ref range...as you can see in Jaydee's reply they are far too low

For good health every cell in tthe body needs to be flooded with T3 by way of an adequate and constant supply....your dose is not achieving this.

T3 is called the active thyroid hormone because once it enters the cells and attaches to T3 receptors it finally gets to work around the body

Low cellular T3 = poor health

It is vital to optimise Vit D, Vit B12, folate and ferritin to support thyroid function.

Bottom line - you need more T4/ levo to raise your FT3 to a level which helps you feel well and resolve symptoms

Research undelines that FT3 followed by FT4 are the important labs but medics focus on TSH, perhaps FT4, which is leaving patients wrongly medicated. Be aware of this.....their thyroid knowledge is poor!

Ask your GP or Endo to raise your levo to 75mcg, hold that dose for at least 6 weeks and test again....at 9am when TSH is highest, 24hours after your last levo dose and before eating breakfast/ drinking coffee. The results will point the way forward

Hope you feel better soon.

Petrahorse profile image
Petrahorse in reply toDippyDame

Thank you SO much for explaining this to me in such an understandable way. I can not tell you how much I appreciate this. I can now finally understand what I need to be working towards.

Petrahorse profile image
Petrahorse in reply toDippyDame

Here are my vitamin results which are within range, other than my raised ferritin levels. I have given blood once to help this.

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