Partners blood test results. : Hi My partner... - Thyroid UK

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Partners blood test results.

Dadof5 profile image
11 Replies

Hi

My partner has been showing lots of the signs of hypothyroidism so I talked her into doing a home test so that see can be forearmed when she sees the doctor. I wonder if you people could take a look and see what you think.

TSH 2.210 mIU/L (.35 - 5.5) 36.1%

Free T4 (fT4) 15.20 pmol/L (11.9 - 21.6) 34.0%

Free T3 (fT3) 3.90 pmol/L (2.8 - 6.5) 29.7%

T4:T3 Ratio 3.897 

Thyroglobulin Antbodies (TgAb) 215 IU/mL (≤ 115)

Thyroid Peroxidase Antibodies (TPO) 9 IU/mL (≤ 34)

It was a Randox Health test and I am not to sure if I have got the ranges correct for the antibodies.

Thanks

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Dadof5 profile image
Dadof5
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11 Replies

Before someone else comes along and comments on results, may I comment on how fortunate your partner is to have you looking out for her 😉

We need family and friends in these difficult times

SeasideSusie profile image
SeasideSusieRemembering

Dadof5

It was a Randox Health test and I am not to sure if I have got the ranges correct for the antibodies.

If they've put ranges for the other tests, have they not put the ranges for the antibody tests?

A few other members have used Randox, I'll try a search to see if anyone else has the antibody ranges.

SeasideSusie profile image
SeasideSusieRemembering

OK, so you've got the right ranges for the antibodies.

A normal healthy person generally has a TSH no higher than 2, often around 1, but that covers about 95% of the population, so the other 5% will have a higher or lower TSH, as you can see from the graph I've included. FT4 in a normal healthy person is generally around half way through range.

Your partner has a slightly elevated TSH (but she could be one of the 5%) and her FT4 is 34% through it's range and nicely balanced with FT3.

Her Tg antibodies are elevated. This can happen in Hashimoto's (autoimmune thyroid disease) although it's probably more common for TPO antibodies to be raised and this is the one the NHS would test, they rarely test Tg antibodies. However, one can have Hashi's with negative TPO antibodies but positive Tg antibodies. Tg antibodies can be raised in Graves disease (overactive) as well as Hashimoto's (underactive).

At the moment those results will not concern her GP and certainly wouldn't suggest hypothyroidism.

As low nutrient levels can have symptoms similar to hypothyroidism she should test

Vit D

B12

Folate

Ferritin

so come back with those results/ranges (include unit of measurement for Vit D and B12) so we can check those out for her too.

Dadof5 profile image
Dadof5 in reply to SeasideSusie

Thank you for your reply. I am going to go to the appointment with her and suggest that they test the vitamins and iron.

I did get the feeling that it wasn’t hypothyroidism. Well at least not bad enough for the doctor to act on.

She has a lot of physical and mental health issues and takes a lot of medication for them so could be one of those causing the problem.

SeasideSusie profile image
SeasideSusieRemembering in reply to Dadof5

They may just offer ferritin, see if you can persuade them to do a full iron panel which includes

Serum iron

Saturation percentage

Total Iron Binding Capacity

Ferritin

This is because you can have a good ferritin level but poor serum iron and saturation levels. The full iron panel would show if she has iron deficiency, testing just ferritin can't show this.

Symptoms of low ferritin include:

◾Weakness

◾Fatigue

◾Difficulty concentrating

◾Poor work productivity

◾Cold hands and feet

◾Poor short-term memory

◾Difficulty remembering names

◾Dizziness

◾Pounding in the ears

◾Shortness of breath

◾Brittle nails

◾Headaches

◾Restless legs

Symptoms of iron deficiency can mirror or coincide with those in thyroid disease. They include:

◾Persistent fatigue

◾Pale skin

◾Shortness of breath

◾Headaches

◾Dizziness

◾Heart palpitations

◾Dry skin

◾Brittle hair and hair loss

◾Swelling or soreness of the tongue or mouth

◾Restless legs

◾Brittle or ridged nails

Iron tests should be done after a 12 hour fast so prepare for this and get the earliest possible appointment rather than go without food during the day (water is allowed)

nhs.uk/common-health-questi...

Examples of blood tests that may require you to fast include:

a fasting blood glucose test (used to test for diabetes) – you may be asked to fast for 8 to 10 hours before the test

an iron blood test (used to diagnose conditions such as iron deficiency anaemia) – you may be asked to fast for 12 hours before the test

For more information about a wider range of blood tests, go to Lab Tests Online.

It would also be useful if she is tested for anaemia, you can have iron deficiency with or without anaemia.

Out of interest, what medication does she take, just in case something is causing these symptoms.

Dadof5 profile image
Dadof5 in reply to SeasideSusie

Are you ready for this!

Pregabablin 600mg

Metformin 1000mg

Rivaroxaban 10mg

Atorvastatin 20mg

Omprezole ?mg

Bisoprolol 5mg

Accrete D3

Paracetamol 2000mg

Dihydrocodein 60mg

Trazadone 150mg

Sertaline 100mg

Cyclizine 50mg

Buspirone ?mg

Obviously that is her daily dosages some are taken in the morning and some at night.

She also has a weekly Semiglutide injection and a monthly Prostap injection

SeasideSusie profile image
SeasideSusieRemembering in reply to Dadof5

OK, so I don't know what they're all for but this is a case of polypharmacy (taking multiple medications) and I wonder if anyone (medical) has checked side effects and/or interactions. Have you spoken to any of her doctors or pharmacist about them?

Have you read the patient information leaflets for all of them? Including the Semiglutide and Prostap injections?

If I were you I'd be spending some time looking into each of these medications, noting the side effects - are any familiar with the symptoms she's experiencing?

Then look for interactions between them, that will take some time but here is a website where you can do this:

go.drugbank.com/drug-intera...

Dadof5 profile image
Dadof5 in reply to SeasideSusie

No we have not really looked any further than if any of the tablets cause weight gain. Will look into it tho as she has recently swapped to a new tablet and the doctor at the sleep clinic(she has sleep apnea and has to use a Cpap machine when sleeping) suggested that her tiredness during the day may be a side effect as the results were good according to her machine.

Like I said I will suggested they test the vitamins as recommended on here and ask for a full iron panel as well.

SlowDragon profile image
SlowDragonAdministrator in reply to Dadof5

High thyroid antibodies confirms autoimmune thyroid disease aka Hashimoto’s

Metformin lowers TSH

cureus.com/articles/50564-e...

omeprazole is a PPI

PPI will lower vitamin levels in gut

gov.uk/drug-safety-update/p...

webmd.com/heartburn-gerd/ne...

pharmacytimes.com/publicati...

PPI and increased risk T2 diabetes

gut.bmj.com/content/early/2...

Iron Deficiency and PPI

medpagetoday.com/resource-c...

futurity.org/anemia-proton-...

onlinelibrary.wiley.com/doi...

sciencedirect.com/science/a...

statins and low thyroid

nhs.uk/conditions/statins/c...

If you have an underactive thyroid (hypothyroidism), treatment may be delayed until this problem is treated. This is because having an underactive thyroid can lead to an increased cholesterol level, and treating hypothyroidism may cause your cholesterol level to decrease, without the need for statins. Statins are also more likely to cause muscle damage in people with an underactive thyroid.

Sleep apnea may be linked to Hashimoto’s

thyroidpharmacist.com/artic...!

Sleep apnea cause or consequence of Hashimoto’s

ncbi.nlm.nih.gov/pmc/articl...

StillEverHopeful profile image
StillEverHopeful

reading you will be asking GP for further blood tests please do make sure you get a copy of the results if you don’t already have online access to them.

Years ago I approached my gp thinking I had anaemia I was told blood tests are ‘fine’ it’s your age but now I can see results online I find my ferritin was bottom of range but mid range for haemoglobin . I now know I am symptomatic if I have low range ferritin & need it above 80 (sorry can’t remember the unit) quite cross I was allowed to suffer unnecessarily for too long. Now I do as you are doing for your wife and dig deeper.

Hope your gp is helpful.

Bearo profile image
Bearo

I can only add that metformin and antacids reduce B12, and that low B12 can produce a lot of symptoms, both physical and neurological.

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