Is it necessary to start treatment with L-thyro... - Thyroid UK

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Is it necessary to start treatment with L-thyroxin 50 μg ?

tryingfortwo profile image
4 Replies

Hi, I'm new to this community and hope to get some advice. While looking into fertility treatment last Sept. I was told that I had elevated TPO antibodies 23.5 IU/ml (normal: <5.6) but TSH was normal at 1.87mIU/l (normal:0.27-4.20).

Then I fell pregnant naurally in January and got my doctor to check these values straight away as I was told to do this should I fall pregnant. The TPO value has shot up to 90.2 kIU/L (normal: up to 34) and TSH had increased to 3.04mIU/l (normal:0.27-4.20). I was referred to an endocrinologist who perscribed L-Thyroxin with Iodine 50 μg.

After two weeks my bloods showed that TPO had increased again to 118 but TSH had decreased to 1.51. I then found out at a rountine scan that my baby had stopped growing at 6 weeks, a missed miscarriage. I stopped the thyroid medication as both doctors prevously said the increased values were probably just been due to being pregnant and I wanted to see if my body would go back to normal.

Three weeks later a blood test at the endocrinologist showed that my TSH level had increased to 4.57, with my TPO value dropping to 52. Now my doctor has perscribed L-Thyroxin 50 μg and advised me to take this for 6 months before going for a check up. 6 months seems like a long time to me - should there not be regular blood controls to check my levels and see if the medication dosage is correct? I'd be very grateful for any advice as I've no experience with thyroid health to date.

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tattybogle profile image
tattybogle

yes it would be much better to have a repeat blood test to check the dose after 6-8 weeks , 3 months at most... you are correct 6 mths is too long.

NHs guidelines officially suggest 3 months ..but many GP will use 6 -8 weeks.

Adults 1.4.3For adults who are taking levothyroxine for primary hypothyroidism, consider measuring TSH every 3 months until the level has stabilised (2 similar measurements within the reference range 3 months apart), and then once a year. nice.org.uk/guidance/ng145/...

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PS I was referred to an endocrinologist who perscribed L-Thyroxin with Iodine 50 μg

does that mean an iodine supplement as well as Levo ? if so ...iodine in what form /at what dose ?

Iodine can have odd or opposing effects of thyroid .. and levo is basically made of iodine anyway (T4 is '4 iodine atoms').. so even though iodine is often recommended in pregnancy supplements , you may not have needed any extra iodine if you were taking levo .

so just in case it's relevant here's a bunch of info on iodine / thyroid . healthunlocked.com/thyroidu... iodine-a-collection-of-useful-information-because-the-search-facility-on-health-unlocked-is-totally-pants

tryingfortwo profile image
tryingfortwo in reply to tattybogle

Hi, thanks a lot for your detailed response. When pregnant, I was prescribed a formulation containing 150 μg of iodine(ions) as the endocrinologist said iodine was very important for the baby.

Thanks for the literature. I have read so much about iodine online, and I find it quite confusing, to be honest. I'll have a look through what you sent when I get a chance.

SlowDragon profile image
SlowDragonAdministrator

ESSENTIAL to test vitamin D, folate, ferritin and B12 levels too

Low vitamin levels extremely common with high thyroid antibodies

Pregnancy guidelines 

thyroiduk.org/having-a-baby-2/

gp-update.co.uk/files/docs/...

See pages 7&8

btf-thyroid.org/Handlers/Do...

Also here - dose increase in levothyroxine as soon as pregnancy test confirms conception 

cuh.nhs.uk/patient-informat...

thyroidpharmacist.com/artic...

Low ferritin, low thyroid levels and risk of miscarriage 

preventmiscarriage.com/iron...

Low iron and hypothyroid 

endocrineweb.com/news/thyro...

Folate and B12 and Neural tube defects and autism 

healthunlocked.com/thyroidu...

tryingfortwo profile image
tryingfortwo in reply to SlowDragon

Thank you for the links. I'll read all of this as soon as I get a chance, thank you so much for sharing.

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