I’m in a place where 75 Levo is too little (bottom range T3 and 4 and TSH nearing 5)
We’re going through IVF and my dose was increased (at my request) to 100. Which felt great for 6 weeks or so. 24th October blood test showed 0.4 TSH and T3 and 4 reaching top quartile.
Yesterday we found out the embryo transfer hadn’t been success (started to implant but stopped) and I can’t helping noticing that I’m feeling slightly over medicated (hot, thyroid “thumping” type sensations that I’ve had before. And I wonder whether this had anything to do with the loss
But I know going back to Levo 75 will be too low - I think I need a split between 100 and 75 to sit where I feel good, which is at the reading levels on 24/10 (any lower TSH wise doesn’t feel right)
do you split the pills?
34 years old
53 kg
female
Written by
Jessica1987
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Jessica so sorry for your troubles.Some folks take 100mcg one day and 75mcg the next day. This is fine to do if that suits you.
My body didn't like different amounts different days so I ended up splitting tablets with a basic pill cutter.
You could also try splitting your dose so take a 50mcg tablet in the morning and the rest of your daily dose at night. This can help as it is gentler on the body and there is not such a high spike when the peak of the dose enters the system.
I’ve dug out a 75microgram pack and they must be different brands then (let me know if the photo doesn’t come through. I’ve been taking 100 on alternative days just because it felt a bit hyper but the latest blood tests don’t show it quite out of range yet. This happened when I moved from 50 to 75, at first I went from high TSH to low (and high T3 and T4 but then it settled down again and within a year, 75 was getting to be too low a dose and that’s where the 100mcg came in. I feel like it only needs a teeny tiny adjustment, as if I went back to 75 it would be too low
Many people find Levothyroxine brands are not interchangeable.
Many patients do NOT get on well with Teva brand of Levothyroxine.
Teva contains mannitol as a filler, which seems to be possible cause of problems. Teva is the only brand that makes 75mcg tablet. So if avoiding Teva for 75mcg dose ask for 25mcg to add to 50mcg or just extra 50mcg tablets to cut in half
But for some people (usually if lactose intolerant, Teva is by far the best option)
Aristo (currently 100mcg only) is lactose free and mannitol free.
Most easily available (and often most easily tolerated) are Mercury Pharma or Accord
Mercury Pharma make 25mcg, 50mcg and 100mcg tablets
Accord only make 50mcg and 100mcg tablets
Accord is also boxed as Almus via Boots, and Northstar 50mcg and 100mcg via Lloyds ....but Accord doesn’t make 25mcg tablets
If a patient reports persistent symptoms when switching between different levothyroxine tablet formulations, consider consistently prescribing a specific product known to be well tolerated by the patient.
Physicians should: 1) alert patients that preparations may be switched at the pharmacy; 2) encourage patients to ask to remain on the same preparation at every pharmacy refill; and 3) make sure patients understand the need to have their TSH retested and the potential for dosing readjusted every time their LT4 preparation is switched (18).
Levothyroxine is an extremely fussy hormone and should always be taken on an empty stomach and then nothing apart from water for at least an hour after
Many people take Levothyroxine soon after waking, but it may be more convenient and perhaps more effective taken at bedtime
No other medication or supplements at same as Levothyroxine, leave at least 2 hour gap.
Some like iron, calcium, magnesium, HRT, omeprazole or vitamin D should be four hours away
(Time gap doesn't apply to Vitamin D mouth spray)
If you normally take levothyroxine at bedtime/in night ...adjust timings as follows prior to blood test
If testing Monday morning, delay Saturday evening dose levothyroxine until Sunday morning. Delay Sunday evening dose levothyroxine until after blood test on Monday morning. Take Monday evening dose levothyroxine as per normal
Similarly if normally splitting your levothyroxine, take whole daily dose 24 hours before test
Increasing number of members find it smoother/more tolerable to split levothyroxine as two smaller doses, half dose waking, half dose at bedtime.
yes, my b12 has always been quite high but it seems to have fallen slightly. I take well woman max as a supplement and there always seems to be such a high RDA of B12. Does having high b12 affect thyroid? Or is there no link.
Yes, strange as all the attention always seems to be peroxidase and thyroglobulin just gets ignored 😂
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