were can i get a private tsi or trab test

[Beeclare]

hi i had a thyroid test in 19 july and after your advice i got my b12 ,vitD, folate , ferrtin done on 27 july

Results

Se holotranscobalamin conc 25.6 pmo1/L >30.0

Confirming B12 deficiency

B12 148.0 ng/L range (200 -910) so low

serm folate 2.6 ug/L range ( 3.0-20.0 )

It say speak to doc and re do test

Vit D 101.0 nmol/L rande ( 50-200)

And bone profile that is normal

I went back to GP and asked if i could have tsi or trab blood test she said that she couldn’t order that test but said the i could have another thyroid test that would confirm Graves’ disease.

today i have had my 5 th B 12 jab and asked for my last blood test results.

the results are 4 August

se thyroid peroxidase Ab con 1000.0 ku/L

Serum folate 3.0ug/L

Can i ask why is the thyroid the same as i have been taking Propythiouracil 200 mg a day since 28 july when i saw the endo who said i had graves and he wants a blood test 8 weeks from this appointment and he said he will review in a virtual clinic and then see me again in six months time strangely I have now had an appointment for the 31st of October with a different doctor.

how much would it cost to have a privet tsi or trab test ?

I live near sutton in surrey so could anyone recommend a place i could have the tests done as i just want to know i i have geaves or Hashimoto’s

Thanking you kindly

X

[SeasideSusie Remembering]

Beeclare

Medichecks do TRAb test but it requires venous blood draw and is quite expensive:

medichecks.com/products/tsh...

Now you've started your B12 injections, have you been prescribed folic acid for your folate deficiency:

serm folate 2.6 ug/L range ( 3.0-20.0 )

Serum folate 3.0ug/L

cks.nice.org.uk/anaemia-b12...

Folate level

◦Serum folate of less than 7 nanomol/L (3 micrograms/L) is used as a guide to indicate folate deficiency.

◦However, there is an indeterminate zone with folate levels of 7–10 nanomol/L (3–4.5 micrograms/L), so low folate should be interpreted as suggestive of deficiency and not diagnostic.

I don't think there's any real doubt that it's folate deficiency.

[Beeclare in reply to SeasideSusie]

Hi i am new to all this and have no knowledge of why folate would be deficient please could you give me some more information x

[SeasideSusie Remembering in reply to Beeclare]

Beeclare

You have B12 deficiency, B12 and Folate work together so it's not uncommon to have Folate deficiency too.

NHS has information here:

nhs.uk/conditions/vitamin-b...

Hashimoto's causes gut/absorption problems which can lead to nutrient deficiencies. It's likely that you have Hashi's and this could be the cause of your deficiencies.

[PurpleNails Administrator]

Medichecks does offer a “Graves antibody test”. It’s £100 (before any discount) and you must have venous draw. (Can’t be done by finger prick)

originalText

It’s name has merged TSI & TRab. TRab measures blocking, neutral & stimulating antibodies whereas TSI measures stimulating only. So the test name is confusing but I believe it’s Trab not TSI. (both are biomarkers for Graves)

The Hospital specialist can order test. The form can be sent to you and you can have blood draw at practice. So can be arranged before a hospital appointment.

What other test confirms Graves? Did GP explain. Other antibodies can confirm autoimmune but only TSI or Trab can confirm graves.

You’ll be due a repeat thyroid function after starting PTU to see if your FT4 & FT3 have reduced appropriately & not too much.

Unless you already have a comparison? Your TPO antibodies are not a measure of thyroid function.

Antibodies also fluctuate. They are the immune system “cleaning up” the thyroid substances which shouldn’t normally circulate outside the thyroid. They cant be treated but are used for diagnosis.

[Beeclare in reply to PurpleNails]

Were are medichecks please ? X

[SeasideSusie Remembering in reply to Beeclare]

Beeclare

I gave you a link to Medichecks TRAb above. Check it out and you will find out how and where you can get a venous blood draw for the test.

[Beeclare in reply to SeasideSusie]

Thanks i have looked it up i am going to try 1 more GP x

[SlowDragon Administrator]

Endocrinologist was sloppy not to have tested TSI or Trab antibodies at consultation

Write and request endocrinologist organise testing immediately

Also you need to update endocrinologist re your extremely low B12 and folate results

[Beeclare in reply to SlowDragon]

The endo saw the B12 results and he told me to go to GP to get treatment for B12 x

[pennyannie]

Hello Beeclare :

Looking back at your previous your blood tests results this looks more like Hashimoto's Auto Immune thyroid disease than Graves Disease, though some people are found to have both, in which case the Graves treatment takes precedence as Graves is considered life threatening if not medicated.

Graves is treated with an anti thyroid drug such as Carbimazole or PTU which put simply, just buys you time, as it blocks you own thyroid hormone production and hopefully this time allows you immune system response to calm down and your antibodies lower.

Generally speaking the antibody blood test is run from the same first blood sample and which ever antibodies are found over range and positive is the medical evidence of diagnosis and on which your treatment plan is based.

Hashimoto's is not medicated as the T3 and T4 do not continue to rise and naturally come back down into range themselves and you may, given time, start to experience symptoms of hypothyroidism as the gland slowly becomes disabled from this AI disease.

It might be worth asking your doctor if there is anything on your medical records confirming this first blood test analysis from the hospital - could it be just be siting in a tray waiting to be input into the system ?

Yes, you can arrange your own blood tests for the Graves antibody - but the NHS are ot obliged to accept this and will run their own, if not done already.

Graves Disease - if you wish to dip in - elaine-moore.com

Hashimoto's - try dipping into - thyroidpharmacist.com