B12 Injections: Hi, I have B12 injection every... - Thyroid UK

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B12 Injections

Benadrove5 profile image
14 Replies

Hi,

I have B12 injection every 3 months i had a routine blood test and my B12 was 1500 when the highest the brackets go is 900 can you advise please as my next B12 injection is not to far away and i'm worried what will happen if it goes too high.

Thank you

T

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Benadrove5 profile image
Benadrove5
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SeasideSusie profile image
SeasideSusieRemembering

Benadrove5

You might be better posting your question on the Pernicious Anaemia Society forum where they are very experienced about B12 injections. My understanding is that when on injections you don't continue to test:

healthunlocked.com/pasoc

Jayneynicks profile image
Jayneynicks

I also have the B12 injections every 3 months for pernicious anaemia although I know others have them for other conditions. You should also have blood tests regularly. You can’t really overdose on B12 and if you have pernicious anaemia then these injections are for life. Speak to your GP if you’re worried xx

Marz profile image
Marz

Testing whilst injecting B12 will skew the results. The test result shows the amount circulating in your blood and not the amount in your cells where it is needed. The Btitish Haematological Society make the point about testing whilst supplementing.

B12 is water soluble so any excess not used by the body will be excreted. I self inject weekly ...

pernicious-anaemia-society....

jamesal0 profile image
jamesal0

Google "japanese b12 levels" theirs top out at 1300. I wouldn't worry too much. A week or two after your shot you'd be back under 1300.

shortytlc profile image
shortytlc

As others have said, no reason to retest once on injections as false result also risk the possibility of surgery stopping b12 treatment as high result (wrong thing to do)

tDR1980 profile image
tDR1980

What should the level be before treatment typically? I had a recent B12 result of 530ng/L but the range on the printout showed 180-2,000 as normal 🤷🏻‍♂️

McPammy profile image
McPammy

I have B12 injections every 3 months. I too had my bloods tested on same day. My b12 was high in the range just as I was to receive my b12 injection. I did get a little concerned. I’ve since learnt that it being too high doesn’t matter as it’s soluble and your body gets rid of what is not required. I’m carrying on as I’d never want the GP to even consider stopping my B12. I also make use of this appointment and get all my thyroid levels checked along with all vitamins and cholesterol. It’s all done in one appointment every 3 months and has been for about 2/3 years now. It’s a really good way of keeping your eye on your levels. My endocrinologist is very pleased I do this too. So far all in range and optimal ✅

CoeliacMum1 profile image
CoeliacMum1

I’ve had B12 injections for almost a decade.As most have said if you have pernicious anaemia (PA) I wouldn’t worry about the levels, unless your GP is concerned of course.

I only have an annual test now for B12 but obviously time these tests to be towards the end of 3months eg nearly due an injection.

My levels are often 700+ approximately towards the end when tested, so me missing an injection would likely make me very tired.

Initially when I started these my surgery got a bit mixed up and said was only to be given a loading on advice of my endocrinologist… by 6 months I was deficient again…I know my surgery thinks (as do many) as supplementing this level shouldn’t now be checked, but I prefer to know, so it’s back on my annual review.

I think we are all different, I do well on 3 months, however my sister could do with them every 2 months to feel better.

I’ve not got into total v active testing of B12

I probably should read up more, but I feel ok, so never bothered to check this out.

I get my total tested (mostly done on NHS) but I assume active is actually more reliable, but probably more expensive.

Read and there’s podcasts on Lifecode GX some can be slow at transportation of vitamin D even though vitamin D levels are often in the ok range, you’re not actually getting the benefit and maybe higher dose is better for that individual … They pointed out for some it’s not about just measuring something that’s circulating it’s how we use and transport these nutrients around our body some of us don’t do this very well regardless of good levels… It’s quite an eye opener what genetics can tell us and you can see what to supplement knowing you have a problem areas and those diet alone should fulfil if you are having a good diverse diet.

I’m only assuming it’s similar situation for Vitamin Bs only difference is Vitamin Bs are water soluble so easily passed out the body if in excess.

Vitamin D is fat soluble, not excreted easily and actually acts like a hormone.

shaws profile image
shawsAdministrator

Have you been diagnosed with Pernicious Anaemia? If so, you should be given a frequent injection by the surgery. Usually it is every three months (quarter).

I now get a monthly jab and GP said I could have as many as I wished.

I usually get a yearly overall B12 blood test.

My mother also had P.A. and GP told her after several years that she needed no more B12 injections. Both myself and sister thought that was a 'good' but unfortunately it was the opposite - it was terrible as Mum developed stomach cancer due to the withdrawal of B12 injections.

Benadrove5 profile image
Benadrove5 in reply to shaws

I'm so sorry to hear that, i dont have pernicious anaemia but have been given B12 injections every 3 months for a few years now and they do make me feel better when i started my test results were 220 but i felt awful one GP said i should have it and the other said it could do more harm than good anyhow i got it and have done ok on it up until this blood test when it came back 1500 the GP has now said to omit it this time unless i feel i need it.I'm totally confused as to if i should have it or not as the figures are high but surely not good to stop and start but someone on here said your body gets rid of what it does'nt need..HELP!!

Jazzw profile image
Jazzw in reply to Benadrove5

Keep having it. It might be awfully difficult to get it reinstated once the doctor stops it. Just say you feel you need it.

It won’t do you any harm at all and more likely will keep your B12 levels in a good place.

High levels, when you have jabs, are not a cause for concern. And they don’t really tell you anything about how much is being absorbed. Don’t let the doctor talk you out of it!

Pernicious anaemia isn’t always easy to diagnose—the test for it isn’t all that reliable. So you may have PA and get a negative result.

Benadrove5 profile image
Benadrove5 in reply to Jazzw

Thank you i do want to carry on with it just a bit nervous of that result and that it may cause harm.

Jazzw profile image
Jazzw in reply to Benadrove5

It won’t harm you. There are people on the PAS forum here who inject daily.

Benadrove5 profile image
Benadrove5 in reply to Jazzw

Thank you

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