How long to feel effects of NDT?: I’ve recently... - Thyroid UK

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How long to feel effects of NDT?

Bellsonit profile image
16 Replies

I’ve recently had an appointment with a consultant who finally diagnosed hashimotos and also confirmed my thyroid is still slightly enlarged. Also that my t3 to t3 conversion isn’t so good.

He’s moved me from 150mg levo to 100mg levo + 30mg NDT (erfa) as he said that would effectively be the same dose.

Would I expect to feel different on an equivalent dose? And how long would it take to feel different? I’m hoping I will at the very least feel more energetic

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Bellsonit profile image
Bellsonit
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16 Replies
shaws profile image
shawsAdministrator

Whatever we've been prescribed to replace thyroid hormones is to try to alleviate any clinical symptoms we may have.

Your Endo sounds a good one as he's prescribed a combination dose.

You have to give a few weeks at least to judge whether or not the dose is suitable.

T3 saturates all of our T3 receptor cells (and is also the 'active thyroid hormone' and then sends out 'waves' throughout the day. Levo (T4) has to change to T3 but not everyone finds levo suitable for them. The brain and heart have the most T3 receptor cells.

my.clevelandclinic.org/heal...

Bellsonit profile image
Bellsonit in reply toshaws

Perfect thanks for this. He did mention about t3 getting into tissues better so that I should feel an improvement, it was just a lot to take in at the time so after a few days on it, it’s got me asking questions.

greygoose profile image
greygoose

How long is a piece of string? It's different for everyone. And, what you are now taking is just a tiny dose of T3 - 4.5 mcg - so might not be enough to make you feel different at all. How long have you been taking it? Did your endo say anything about increasing the NDT with time?

Bellsonit profile image
Bellsonit in reply togreygoose

Hi thanks for this. Since last Friday so not long at all. Things are so frantic at the moment work wise and I’m shattered - so sometimes when I’m in that state I don’t always notice a step change in how I feel, and I guess after years of levo and changes to that I never really feel that great, unless it’s reduced and then I feel horrific . He didn’t mention increasing but will see me again in 6 weeks to see how things are progressing.

greygoose profile image
greygoose in reply toBellsonit

OK, so probably not long enough to feel any difference. I have to say that some people feel better almost immediately, but other it can take weeks. And, don't worry if you start to feel better, and then feel bad again. This is normal and it just means you're ready for an increase in dose. :)

Bellsonit profile image
Bellsonit in reply togreygoose

Thanks - fingers crossed then and when things settle down I might get an opportunity to reflect on how I’m feeling

Bellsonit profile image
Bellsonit in reply toBellsonit

I’m just so grateful to try something different. He’s prescribed t3 before but is a lot more comfortable with ndt as it doesn’t create a spike.

greygoose profile image
greygoose in reply toBellsonit

Not sure he's right on that one, but still. Glad you're getting to try something different. :)

Bellsonit profile image
Bellsonit in reply togreygoose

I don’t know so much about either aside from what I’ve read on here - but for some reason he wanted to use Ndt but he has prescribed t3 before according to the endo list .

greygoose profile image
greygoose in reply toBellsonit

Well, let's hope it works. :)

Bellsonit profile image
Bellsonit in reply togreygoose

Yeah fingers crossed indeed. Thanks for the advice

greygoose profile image
greygoose in reply toBellsonit

You're welcome. :)

SlowDragon profile image
SlowDragonAdministrator

Were vitamin D, folate, ferritin and B12 levels tested

Levels should be tested at least annually

Vitamin D twice a year when supplementing

What vitamin supplements are you currently taking

As you have Hashimoto’s are you on strictly gluten free diet or dairy free diet

Bellsonit profile image
Bellsonit in reply toSlowDragon

Hi yes I’ve had testing on vit d which was pretty abysmal at 31! He’s got me on 4000 per day. Folate on nhs was 6.2 but I’m not sure of the range

Healthscreen - Ferritin - 92 (range 13-150)

Healthscree. - B12 - 107 (range25-165)

Interestingly the nhs reads of ferritin and b12 wee lower but they didn’t tell me the ranges.

Bellsonit profile image
Bellsonit in reply toSlowDragon

And I’ve not been reducing dairy, but have significantly reduced carbs generally

Bellsonit profile image
Bellsonit in reply toBellsonit

I do actually feel better with less carbs, so I would imagine my gluten intake is minimal as most carbs I have will be from vegetables and potatoes. When I have a big lot of anything like bread I feel lethargic and puffy

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