Tinnitus and Vitamin D are both frequently mentioned here. Add in the TSH and this looks very interesting.
Although I have long had tinnitus (and, as I type, it is driving me a bit bonkers), I have never noticed any obvious relationship with taking vitamin D supplements nor with levothyroxine dose.
I'll just go and take the vitamin D I didn't get from the sun today.
The role of vitamin D in subjective tinnitus—A case-control study
• Magdalena Nowaczewska ,
• Stanisław Osiński,
• Maria Marzec,
• Michał Wiciński,
• Katarzyna Bilicka,
• Wojciech Kaźmierczak
• Published: August 18, 2021
• doi.org/10.1371/journal.pon...
Abstract
Regarding the high prevalence of vitamin D (25(OH)D) deficiency in the population and its possible association with ear diseases, we aimed to investigate the 25(OH)Dserum level in patients with subjective, nonpulsating tinnitus and its effect on tinnitus severity. The study included 201 tinnitus patients and 99 controls. Patient clinical information, including tinnitus characteristics and severity according to Tinnitus Handicap Inventory (THI), loudness assessed by Visual Analogue Scale (VAS), audiometry, and the blood level of vitamin D, was recorded. The level of 25(OH)D in tinnitus patients was significantly decreased compared with the controls (19.86 ± 7.53 and 27.43 ± 8.85 ng/ml, respectively; P value < 0.0001). More patients in the tinnitus group were deficient in vitamin D, compared with the controls (50.7% vs. 22.2% respectively, p < 0.0001). Tinnitus patients with a lower serum level of 25(OH)D (≤15 ng/dl) were significantly younger, had a higher degree of tinnitus severity measured with THI and VAS scales, had higher triglyceride and TSH levels, and a lower HDL level compared with individuals who had higher 25(OH)D level (>15 ng/dl). There was a strong correlation between the 25(OH)D level and THI. Our findings suggest that a large proportion of tinnitus patients suffers from vitamin D deficiency and that the vitamin D level correlates with tinnitus impact. We recommend a vitamin D assessment for all tinnitus patients.
Full paper freely accessible here: