Confused….cortisol saliva test results

[fred1e]

Background : I have central hypothyroidism with Hashi antibodies too, I am also coeliac

I am currently on 125mcg thyroxine, free T4/T3 levels are rising (TSH low, but ignoring as is central issue)

High am blood cortisol (620), so decided to do a saliva test for cortisol/DHEA, and chose Cambridge nutrition as recommended by thyroid uk and do 2 dhea measurements…..results in photo.

So….despite high blood cortisol, saliva am looks normal , but by 1pm measure is rock bottom and stays there…..?

….most people with that sort of curve seem to have a low dhea….mine is normal, with the ratio to cortisol being the reverse of most people with adrenal “insufficiency “

Any thoughts/experiences/experts.???

Thanks.

[fred1e]

This might be of interest to others with a high 9am serum cortisol, but low free salivary cortisol, as discusses the link between thyroid and binding globulins:pubmed.ncbi.nlm.nih.gov/774...