Tsh surpressed by Other medication.

[Yeswithasmile]

Hello.

I wonder if I could get some advice about my husbands thyroid?

He takes a drug called Roprinole.

It’s is noted that it surpresses the pituitary regarding Prolactin and he now has none. However his TSH is 0.9 (0.27 - 4.2) but his FT4 is 12.6 (12-24) and his ft3 4.8 (3.2 - 6.8). So I am assuming it surpresses the gland completely.

My question is do you think this is a case of an under active thyroid here? I realise his t3 is fairly good considering.

His cholesterol is high too. He is prediabetic. His vitamins were middle of the ranges.

Thank you for any advice you may have.

[diogenes Remembering]

Though ropirinole suppresses prolactin, it is doesn't seem to affect TSH. Your TSH results look OK. The drug is being discontinued from Glaxo Smithkline. Its main use is in restless leg syndrome suppression, It acts like dopamine in inhibiting the incorrect brain function that is responsible for restless leg.

[Yeswithasmile in reply to diogenes]

Yes. It is also prescribed for a Parkinson’s. I had noted that it is to be discontinued but it hasn’t yet. My concern is that the tsh is not surpressed, no, but quite low in the range for a t4 of 12.6. It seemed like it should be higher. I simply concerned that all symptoms not be put under one illness. I thought I would retest in 3 months. Thanks for the reply.

[KAgolf in reply to diogenes]

great--so what are those of us who use Ropinirole for RLS supposed to do?you cannot imagine how awful it is sometimes, especially if you are so tired and you just want to relax but have to stand up to get relief.....awful and debilitating

[Terricotta]

Hi Yeswithasmile

I don't have an answer to this, but coincidentally, only today I've been looking at prolactin, dopamine and thyroid issues. The following might be of interest:

ncbi.nlm.nih.gov/pmc/articl...

In a nutshell - prolactin, dopamine and the thyroid axis have a close relationship. If the roprinole is increasing dopamine production, the thyroid hormone axis can be affected. Prolactin will be reduced.

[Yeswithasmile in reply to Terricotta]

Thanks I will read. It’s very kind of you.

His thyroid is fluctuating a lot and his prolactin is on the floor. Basically though the more I look into Parkinson’s and thyroid as separate subjects they do often overlap. Just showing how everything is intertwined. We all know it is but once you start researching stuff I am often bowled over by just how much. Maybe this is really obvious to most and I should have just paid more attention in school?? 🤣

[Terricotta in reply to Yeswithasmile]

Hi Yeswithasmile. It's probably not even obvious to the doctors. I think the activity of the amino acid, tyrosine is involved here, in relation to dopamine. Both have a knock-on affect on prolactin and thyroid it seems. Anyway, I'm not an expert and wouldn't know where to start in explaining any of this to a doctor, so apologies if I've overstepped the mark.

[Yeswithasmile in reply to Terricotta]

Oh not at all!! Grateful for your input. Thanks ever so. It definitely spurred me back onto his issues again. 😊