Still unwell and not sure if results are ok. He... - Thyroid UK

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Still unwell and not sure if results are ok. Help again please.

Dunawori146 profile image
11 Replies

If you don’t mind helping me again, I would very much value your opinion. I have given as much information as I think you might need but please do ask if you have any questions. Also, if you don’t think this post is appropriate here because it is not directly related to Thyroid, I can remove it

I need to go back to my GP because on average I get sick at least 1 day every fortnight but I feel that I will be fobbed off yet again, so I want to go armed with knowledge but I’m finding it difficult to research online

After my Blue Horizon blood tests showed raised Ferritin and CRP levels, I went to the GP for further tests (she wasn’t too happy that I had been elsewhere). When the results were back, I was told by the receptionist that they were “Abnormal but no action to take.” (CRP 10 mg/L. - ESR 28 mm/h)

The GP did eventually give me an extra 25mcg of Levothyroxine

I know that my test results can vary. Previously, I have even been hospitalised twice and given intravenous antibiotics (3 for 8 days (Jan 2017) & 4 for 5 days (Oct 2019)) because my infection makers were high but I was discharged without a conclusive diagnosis.

In Aug 2019 it was found that I have hypogammaglobulinemia - IgM 0.2 g/L & IgA 0.4 g/L. Although, amyloidosis has been mentioned, no conclusive diagnosis/cause has been reached.

I also have had ‘deranged’ liver function results since at least 2013. The serum gamma GT level ranges from 120 u/L – 749 u/L. (Sept 2020 – 332 u/L)

I take Tegretol for Bipolar so it has always been expected but because of feeling poorly for so long, I am worrying about now. The GP almost expects it now so they never mention it. (by-the-way I never drink alcohol)

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Jazzw profile image
Jazzw

Hi Dunawori146 :) I’ve taken the liberty of copying your last set of results across from 8 weeks ago. And it’s my understanding you were (just about able) to persuade your doctor to raise your Levo dosage by another 25mcg?

I think it’s possible you need another raise in Levo dosage but your doctor may be reluctant to do another test (they ought to, given you paid for the last one). Worth asking!

I wouldn’t worry too much about the ferritin in and of itself. It’s only slightly elevated, which happens when there’s inflammation and we know there’s something inflammatory going on because of your raised CRP.

I would imagine your doctor’s taking a “watch and wait” approach to your raised CRP as it can be due to something simple like a minor infection and not necessarily indicative of something serious. But if it stays high then ideally your doctor should investigate.

Have you been supplementing B vitamins and Vit D over the last few weeks?

Dunawori profile image
Dunawori in reply to Jazzw

Thank you very much for this information, I only ever find out things on this site, it's brilliant !I will go back to the doctor to discuss what you have suggested.

Recently I've been taking vitamin D and a multivitamin

Thank you again for the advice

Jazzw profile image
Jazzw in reply to Dunawori

You’re welcome. :)

I’ve been reading your @Dunawori146 profile since I replied and see you’ve got possible Crohns/ulcerative colitis(?) going on (poor you!), so flares of that are probably what’s spiking your CRP and ferritin levels.

But chronic undermedication for your thyroid condition isn’t going to make things any easier on your bowel—in fact, optimal medication is a must, so that everything moves through as it should. I think doctors seriously underestimate the importance of treating thyroid issues—when you consider that thyroid hormone is essential for every cell in your body, it makes sense just how much can go wrong if you don’t have enough of it!

SlowDragon profile image
SlowDragonAdministrator in reply to Dunawori

How much vitamin D are you currently taking

Need to retest twice year on vitamin D supplements

via NHS postal kit £29

vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function. There’s a version made that also contains vitamin K2 Mk7

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need,

Low folate and low B12

Rather than taking a multivitamin (too little of what we need) you might find it more beneficial to be taking vitamin B complex for your low folate and low B12

a good quality daily vitamin B complex, one with folate in (not folic acid) may be beneficial.

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

chriskresser.com/folate-vs-...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Igennus Super B is good quality and cheap vitamin B complex. Contains folate. Full dose is two tablets per day. Many/most people may only need one tablet per day. Certainly only start on one per day (or even half tablet per day for first couple of weeks)

Or Thorne Basic B is another option that contain folate, but is large capsule

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

Low B12 symptoms

b12deficiency.info/signs-an...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a B12 supplement as well as a B Complex (to balance all the B vitamins) initially for first 2-4 months, then once your serum B12 is over 500 (or Active B12 level has reached 70), stop the B12 and just carry on with the B Complex.

B12 sublingual lozenges

amazon.co.uk/Jarrow-Methylc...

cytoplan.co.uk/shop-by-prod...

healthunlocked.com/thyroidu...

SlowDragon profile image
SlowDragonAdministrator

In Aug 2019 it was found that I have hypogammaglobulinemia - IgM 0.2 g/L & IgA 0.4 g/L.

Being Hypothyroid is frequently linked to hypogammaglobulinemia

scielo.br/scielo.php?script...

Hypothyroidism was identified in 4/8 (50%) patients.

SlowDragon profile image
SlowDragonAdministrator

Tegretol and being hypothyroid

healthline.com/health/hypot...

Prescription medicines that can interact with levothyroxine include:

antiseizure drugs, such as phenytoin (Dilantin),

carbamazepine (Tegretol)

Dunawori profile image
Dunawori in reply to SlowDragon

Gosh... this is such a lot to take in. I need to digest what you say.

I did buy the Vitamin D mouth spray after you recommended it. I do have a test so I will do a test now.

Thank you for all the information regarding vitamin B & B12 (and folate).

My GP didn't wish to engage in any discussion about them (to be fair I only had a quick phone consultation when I asked for a blood test but like I said she wasn't happy with me)

Thank you for all this very useful information

Dunawori profile image
Dunawori in reply to Dunawori

Tegretol and being hypothyroid

This is very interesting, I will certainly read this

Being Hypothyroid is frequently linked to hypogammaglobulinemia

No one has mentioned this to me, so thank you for this

SlowDragon profile image
SlowDragonAdministrator in reply to Dunawori

Always worth goggling different issues and hypothyroidism

Lack of thyroid hormone affects every single cell

Dunawori146 profile image
Dunawori146 in reply to SlowDragon

Yes, thank you, I'm realising that more and more. For too many years I have just put my trust and belief in the doctors. I have always believed that they had my best interest at heart, without question.

SlowDragon profile image
SlowDragonAdministrator in reply to Dunawori146

Sadly thyroid disease is extremely misunderstood

There’s over 117,000 members on here. .....

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