Hi I am new to this and wondering if anyone could shed any light. I've just had an autoimmune test and come back that I have TPO antibodies that are level 10.6. I also suffer with low haemoglobin levels, really bad leg aches etc
Haematocrit 0.369
Mean cell haemoglobin level 25.1 pg
Mean cell haemoglobin concentration 309.0 g/L
Any advice is really appreciated
Written by
DMsentance
To view profiles and participate in discussions please or .
To be able to interpret your results and help you, can you please provide the reference ranges that come with your results. Ranges vary from lab to lab, for example TPO antibody range can be 0-34, 0-50 or 0-60 and that's just some of the ranges we see here.
Your TPO negatives are within range therefore they are negative for autoimmune thyroid disease as far as that test is concerned. However, we can have negative TPO antibodies but positive Thyroglobulin antibodies so it would wise to have those checked. Also, we can have negative antibodies but still have Hashimoto's.
All your other results are below range and should be discussed with your GP, they may possibly indicate anaemia (I am not diagnosing, I am not medically qualified). Do you have any other results - haemoglobin, iron panel, B12, folate?
If you do then list them to discuss with your GP and ask for testing for B12 deficiency and Pernicious Anaemia. Do not take any B12 supplements or folic acid/folate/B Complex supplements before further testing of B12 as this will mask signs of B12 deficiency and skew results.
So it might be worth repeating your B12 test.
Serum folate level 3.9 ug/L [3.1 - 20.5]
Extremely low, just in range, possibly suggestive of folate deficiency - see
◦Serum folate of less than 7 nanomol/L (3 micrograms/L) is used as a guide to indicate folate deficiency.
◦However, there is an indeterminate zone with folate levels of 7–10 nanomol/L (3–4.5 micrograms/L), so low folate should be interpreted as suggestive of deficiency and not diagnostic.
I would ask for folate to also be retested.
Serum ferritin level 12 ug/L [10.0 - 204.0]
Absolutely dire. Possibly suggestive of iron deficiency anaemia. An iron panel needs to be done.
Definitely repeat ferritin test now unless you have had iron supplements and are being monitored regularly.
Please see above.
After interpreting your TPO result I mentioned above in reply to your test results posted in your opening post:
"All your other results are below range and should be discussed with your GP, they may possibly indicate anaemia"
There is a heavy auto immune family history aswel.
And it's possible that you do have Hashi's as I said
However, we can have negative TPO antibodies but positive Thyroglobulin antibodies so it would wise to have those checked. Also, we can have negative antibodies but still have Hashimoto's.
and that could be the reason for your dire nutrient levels, but you need up to date results, you can't rely on old results.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.