Tiromel Cynomel T3 Only

[Arabella33]

Hello everyone. I’m swapping tiromel to cynomel Mexico. Is this a straight swap or is one stronger than the other? What are possible reactions to both?

[EbonyEvans]

It’s how your body reacts to nee meds. The extra ingredients may or may not agree with you. Cynomel works for me but I have had to take less Tiromel as I’ve found it really strong and gave me headaches (I wasn’t dehydrated but I drank loads of water and it helped)

[Arabella33 in reply to EbonyEvans]

You had to take less tiromel ? I’m on quite a lot of tiromel and so I’m trying cynomel as I hear it’s stronger. The Mexican one. I’m swapping slowly as I don’t want and adverse side effects ....

[EbonyEvans in reply to Arabella33]

I cut it into quarters and took 18.25 mcg (3/4)

[Arabella33 in reply to EbonyEvans]

Sorry you are saying that tiromel is stronger than cynomel Mexico ?

How much of each did you take overall ?

[EbonyEvans in reply to Arabella33]

No. My personal experience is that Tiromel is stronger for me personally. I generally take 25 mcg a day of uni Pharma. But when I took Tiromel I needed 1/4 less tablet as I find it strong.

[Arabella33 in reply to EbonyEvans]

Thank you Ebony, that’s very helpful

[DippyDame]

Why are you taking T3 only? I see in one of your posts that you were taking 125mcg which is a large dose unless you have a form of thyroid hormone resistance. . I doubt that dose was prescribed!

I take it that you understand the dangers of overdosing with T3.

Do you regularly monitor heart rate, basal temperature and blood pressure?

How much do you currently take?

Sorry, I know you didn't ask about this but T3 must be understood and treated with respect. T3-only is the last resort.

You seem to be making fairly quick changes to your dosing regime, be careful that you don't risk " confusing" your body

You may find this ebook interesting it is available on Amazon for £3.56 or free if you have Amazon Prime. It is called "Impaired Sensitivity to Thyroid Hormone (Thyroid Hormone Resistance)" by Hugh A Hamilton. It refers to the work of Dr John Lowe among other respected authors.

To your question...

Depending on availability I've swapped between these brands with no obvious problems.... I need a large single dose so perhaps that makes a difference.I have read that Cynomel is stronger than Tiromel but, to quote an often repeated phrase on here, "we are all different"!

[Arabella33 in reply to DippyDame]

I didn’t do well on t4 it made me feel ill. I’m on 150 mcg tiromel still have brain fog and insomnia. My t3 has been prescribed yes I’m working with a dr. I tried to move it to one dose in the morning but it made my heart rise when i walked. I had to stop taking it for 2 days and split the dose again.

I have low rhr of 55 now risen from 31 still have insomnia brain fog and constipation. Basal temp always low.

My labs still show low t3 6.29 (3.1-6.8 )

I have been doing this a while.

I’m not sure what to do next as my symptoms haven’t resolved?

I did a saliva cortisol test which showed MODERATELY low at noon and 4pm and a supprt these times with 5 x ACE

[DippyDame in reply to Arabella33]

A medic prescribing a supraphysiolgical dose of 150mcg T3 ...surprising! Are you in the UK?

Also, did your medic suggest ACE?

You appear either to be overdosed or suffering from hormone resistance....and looking at your earlier labs I suspect the former.

Your dosing regime has been rather chaotic as I suggested above.

Are you aware of the converse effect of T3, that is when too much hormone can result in similar symptoms to undermedication?

Who told you your labs are low?

"My labs still show low t3 6.29 (3.1-6.8 )"

This is not a low reading!

Your FT3 is 86.22% through the ref range when it should be approaching 75%, you appear to be overmedicated.

I'm not a medic but have travelled a long bumpy road to recovery, as good as I can hope for at age 75, and in your shoes I would be questioning my medic's knowledge of thyroid disease.... as described in your previous posts.

In the past when in a similar situation I stopped all T3 ( I had reached 200mcg) for 4 days and then started again with 50mcg and very slowly added 6.25mcg ( from 25mcg tablet) every 6 weeks until I found my therapeutic dose (now 100mcg). If you titrate too quickly you will miss that spot!

I have no scientific proof to hand for this but I had been fine on 200mcg - until I wasn't - and I suspect the large dose "kick-started" some of the T3 receptors resulting in the need for a smaller dose.

Re heart rate -

Have you had an ECG?

Have you had an Echocardiogram?

I had both along the way and thankfully my heart is fine.

I can only offer you my experience, not my advice, but I hear what you are saying and I suggest you need to seriously reconsider your T3 dosing regime and also to revisit your cortisol levels.

Good luck

DD

[Arabella33]

My thyroid specialist gp advised that I continue raising until symptom relief when on 75mcg and looking at symptoms and labs. He is American based in Ireland. I raised 6.25 mcg until I got to 125 then held for four weeks. I have felt slightly better each time I raised. I am U.K. yes. I just surprised that it’s taking so much and don’t really want to be on so much.

He suggested ACE as well yes as a forward thinking Dr although I already knew I would need support for only slightly low cortisol twice per day. We have also done a gut test and the tickplex plus for Lyme and co factors

How can an overdose of t3 cause slow heart rate and constipation ? I don’t think this is the case. Which symptoms are you referring to when you say they are the same as underdosing? Although I’d prefer to be on a smaller dose some people need larger doses to feel well.

What are the dangers of overdosing with t3?

Thyroid labs according to sttm and other s should be top of range on t3 only or over. 75% is on t4/t3. I’m surprised that you say I’m overdosed when I have symptoms of underdosing, and labs that are not even over range. Many people need to be over runs range with no symptoms of thyrotoxicosis to feel well it’s individual.

I have had an echocardiogram and stress test due to being admitted with a low heart rate. My heart is fine thankfully.

I don’t feel my dosing has been chaotic I’ve taken time to plan things through and revise symptoms and hold before labs. I do disagree slightly with holding for so long and do have some urgency to resolve brain fog. I’m in a considerable amour of distress. All hyper people tend to report anxiety rather than brain fog in my experience.

How would you suggest working on cortisol if it’s slightly low. It’s low overnight and wakes me up !

Thank you for sharing your health journey and experience it’s is helpful and appreciated .