Testosterone HRT with Levothyroxine : Hi wise... - Thyroid UK

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Testosterone HRT with Levothyroxine

TiredMummy profile image
6 Replies

Hi wise posters, I’m on testosterone as part of HRT & take Levothyroxine in the mornings which suits me best. Does anyone know if testosterone interferes with Levothyroxine? If so, I should try applying the testosterone gel at night & hope it doesn’t make my insomnia worse. I’ve only just started testosterone gel so I know that isn’t the cause of my insomnia at the moment any way!

Thanks 😊

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TiredMummy
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SlowDragon profile image
SlowDragonAdministrator

When were vitamin D, folate, ferritin and B12 last tested

What vitamin supplements are you currently taking

Insomnia often linked to low vitamin D and/or low Ft3

Are you currently taking any T3?

If yes, have you tried taking last dose at bedtime, often helps improve sleep

TiredMummy profile image
TiredMummy in reply toSlowDragon

All vitamin levels are fine but good call & thanks for checking. I’m regularly tested as seeing functional nutritionist. Ive recently started to suffer from RT3 since I changed my HRT. I’ve just gone back onto my old HRT which I felt much better on but wondering whether testosterone is best taken at night & if it interferes with Levo or not?

SlowDragon profile image
SlowDragonAdministrator in reply toTiredMummy

Hopefully any other members who use testosterone may be able to advise

Min789 profile image
Min789

I use testosterone gel in the morning, I rub the gel onto my skin usually after a shower. I have never noticed any intereference with levothyroxine in the 10 years I have been using it.

Kiwidel profile image
Kiwidel

I’m on NDT not levothyroxine, but I use a testosterone cream at night and take my NDT early morning and it’s been fine. I think because the testosterone is being applied to your skin there should be less risk of negative interaction.Perhaps try magnesium for your insomnia.

TiredMummy profile image
TiredMummy in reply toKiwidel

Interesting that you use the gel at night. I guess it will be trial & error!

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