Just had these results from GP and need to know what I need to do, please. Currently on 80mcg Thybon Henning from Germany in three doses from 7.30am. No Levo. He suggests a 10% reduction.
Feeling reasonably well. Losing a little weight which needs to reduce about stone more. That would still be 7 pounds more than weight 12 years agoStill a bit lethargic which mostly comes around 2pm and heady. Could that be overdose?
Help, please! Lynn
TSH <0.01 (0.27-4.2)
T4 <0.5 (12-22)
T3 8.6 (3.6-6.8)
Your dose is quite high, normally 40 to 60 mcg is recommended by the manufacturers. The fT3 figure is difficult to interpret because it depends on how much time you leave between a dose and taking the blood. Your TSH is very low and if it is kept this low for some time your pituitary will down-regulate leading to a permantely low TSH. This is undesirable because TSH promotes T4 to T3 conversion.
I would try making do on 60 mcg. I find a bedtime dose of L-T3 helps with better sleep and a clearer head the next day. It may be you need 80 mcg but try to get by on lower doses. Hypothyroids tend not to lose the weight they put on, don't use weight as a guide to dosage. I find daily long walks the best way to lose weight, by accident I was just exercising.
Thanks for your comments, Jim.
Know my dose seems high but have read on here that some take well-over 100. Fasting test with gap as recommended on here. Still, in light of results, GP wants me to reduce by 10 per cent. Before do that, I’m hoping for a few more comments.
Never found any correlation mentioned on line about tsh having any effect on conversion. Been searching. Where did you get that fact from, please?
Still finding hard to understand why tsh would be important if one is taking t3 because one doesn’t convert. As previously told on here, it’s not relevant. But mine is very low, I agree.
Sorry, but I do see my weight loss or not as a symptom of how the t3 is working, because it should show that my metabolism is working correctly. It goes without saying that how I feel is even more important.
Regarding weight, exercise doesn’t help me lose anything. Of course, if I had been sedentary before, it may have made a difference, by I’m always on the go, even if I don’t go for walks. Unfortunately, I don’t have time apart from gardening and looking after a total disabled husband! But then, we’re all different.
The experience of a large number of patients is that they tend not to lose the weight they put on when hypothyroid. They lose some weight when adequately medicated but do not get back to their original weight.
Ideally you would be able to take some levothyroxine and reduce your liothyronine. This would allow your body to work more naturally and use deiodinase to regulate local T3 levels. TSH has other actions that are little understood such as s role in bone formation. So, ideally we would have a normal TSH.
The role of TSH in deiodinase is complex, I have written some notes here ibshypo.com/index.php/tsh-r... .
Have you tried loading? Ie taking your T3 in one or two hits a day? I’d play with that before you make changes.
Are your Vits and minerals optimal?
I would ignore TSH now that you are almost certainly replacing all your Thyriod needs. It’s all very well to know that TSH helps conversion and bone formation but that’s a bonus that most of us who replace just can’t utilise. If we raise our TSH we don’t get enough Thyroxine so what’s a girl to do? My TSH is 0.005. Finally I can live life. I just can’t worry about TSH, any pros of a higher TSH just don’t out way the cons.
If you need a supraphysiological dose of liothyronine then there's not much you can do. However, if a lower dose makes little or no difference then it makes sense, you reduce chances or osteoporosis or atrial fibrillation and stroke. Many of us have to have a very low TSH but it does carry significant risks, when the hormone dose is above normal levels. You may be between a rock and a hard place but there may be scope for manovure.
I took levo for many years - around 20 - and originally was OK on 125 but then went back to feeling grim- no energy, get up and go etc, with weight piling on and osteoporosis. Finally saw endo who suggested t3. Gradually reduced levo and now don’t take any. Don’t understand why I need it if I don’t convert. Nor do I understand why I should worry about negligible tsh. Sorry, tried to read your blog but my brain wasn’t up to it! Lynn
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