Can anyone shed light on these Medichecks Neutrophil/Globulin blood results please?

Hi All

I am hypo, on NDT and my main symptom is muscle aches, which I've had since Dec 16 and are progressing.

And I'd love to find an answer for them.

Searching for an answer, I forwarded these Medichecks Neutrophil/Globulin blood results to my GP last week and had the tel appointment today.

The Medichecks doctors always say that the under range Neutrophil and over range Globulin results are a sign of a recent infection.

However, my GP did not seem concerned enough to investigate further.

So, can I ask if these consistently low/under range Neutrophil and high/over range Globulin results warrant further investigation?

NEUTROPHIL/GLOBULIN RESULTS

23 Feb 19

Neutrophil 2.22 (2 - 7.5)

Globulin. 39.2. ( 19 - 35)

(All below ranges are as above)

5 July 19

Neutrophil. 2.2

GLobulin. 33

20 Sept 19.

Neutrophil. 2.5

Globulin. 33.3

10 Jan 20.

Neutrophil. 1.64

Globulin. 38.3

6 July 20.

Neutrophil 1.71

Globulin. 37.8

Any ideas gratefully received, as usual.

Thanks

Alps

[Jazzw]

I’m not a doctor, just an amateur sleuth but I’d guess you’ve probably got a low grade infection and / or an autoimmune issue going on. An autoimmune issue could just be your thyroid problem—do you have Hashi’s? Potentially you have another autoimmune issue to go with it—autoimmune diseases do tend to hunt in packs... Whereas a low grade infection could be something like a tooth slowly decaying—had any root canals or similar? That’s just an example. I’ve had problems with a root canalled tooth for some time which I swear led to all kinds of other aches and pains—finally had the offending tooth out about a month ago and I swear that other niggling issues I’ve had for a while are starting to improve.

I’d say that if it was something more serious that the levels would be significantly worse. You’ve said in previous posts that your liver and kidney tests are ok, so that’s good news.

[Hidden in reply to Jazzw]

Thanks jazzw for your helpful points

Yes I have Hashis with both TGO and TPO well over the range

But, I've just found some old Neutrophil/ Globulin results from before Dec 16, when I wasn't Hypo, and they too are the same pattern as now

Not had any dental work for 2 years, when I just had an old filling redone

Pleased to note that your recent dental work helped

Alps

[Marymary7]

Are you sure your thyroid results are optimal. My shoulders and arms ache or feel like pulled muscles if I don't take care with various thyroid levels. I take vitamin supplements too. Even the strength in my hands for opening jars etc is effected and can feel sprained.

What about your thyroid antibodies ? Good advice from Jazzw too. I often wonder about the amount of mercury I've consumed from my broken fillings and dental work.

I hope you can solve the mysteries and gain your health .

[Sarfran in reply to Marymary7]

Gosh, we could be twins! I also get weak legs and my gluteus maximus/maximii 🤔 aren't always as maximus as they should be.

[Hidden in reply to Sarfran]

Hi sarfran

Hope your aches improve!

Alps

[Workingitout in reply to Marymary7]

I have Hashi’s and autoimmune disease with the same aches and weakness in my shoulders and down the front of my arms, sore thumb joints and hips and mortens neuroma in my feet. I am 57, eat well and exercise regularly and am taking supplements and now having acupuncture. I think my thumb joints are similar to most people of my age but the shoulder aches are different. I do wonder if it’s a result of a virus or maybe side effect of Levothyroxine?

[Hidden in reply to Marymary7]

Thanks marymary7

My TSH is 0.1 (0.22-4.20)

FT4 12 (12-22)

So, TSH is very low and FT4 too low?

I'm on 1.5 NDT

Thanks

Alps

[Marymary7 in reply to Hidden]

Yes that t4 is too low. As you can see it's at the bottom of the range. Need the T3 levels and ranges too, also thyroid antibodies. You also need high enough vitamin D3 and k2 plus Magnesium plus other supplements which others are good at?

SeasideSusie gives excellent advice.

[Hidden in reply to Marymary7]

Thank you marymary7

I take 15 ug D, 200mcg K2 Mk 7 and 100 Mag

I'm minded to add a little bit of Levo to bring the FT4 up?

Thanks

Alps

[Marymary7 in reply to Hidden]

You need to know the T3 levels that's the crucial bit.

[SlowDragon Administrator in reply to Hidden]

Ft4 is frequently low when on a NDT ...most important results is always Ft3

Testing should be done as early as possible in morning before eating or drinking anything other than water and last 1/3rd or 1/2 of daily dose NDT 8-12 hours before test

Is this how you do your tests?

[Hidden in reply to SlowDragon]

Yes, I always do a fasting bloods, with just plenty of water

And take the NDT just after

Thanks

Alps

[SlowDragon Administrator in reply to Hidden]

Where’s the Ft3 result?

[Hidden in reply to SlowDragon]

July 3

FT3 4.63 (3.1-6.8)

TGO. 209 (<115)

TPO. 56. (<34)

Thanks

Alps

[SlowDragon Administrator in reply to Hidden]

So this was all same test ?

TSH is 0.1 (0.22-4.20)

FT4 12 (12-22)

FT3 4.63 (3.1-6.8)

Was last half or third of daily dose of NDT 8-12 hours before test

[Hidden in reply to SlowDragon]

Hi

Last NDT taken 24 hours before test

Then took NDT again straight after test

Thanks

Alps

[SlowDragon Administrator in reply to Hidden]

Bloods should be tested by splitting dose day before test and taking 1/2 or 1/3rd of daily dose 8-12 hours before test

Your Ft3 will be false low result if last dose 24 hours before testing

Many people find it better to split NDT into two doses everyday

[Hidden in reply to SlowDragon]

Thanks for the tip

Wasn't aware of that

Will split NDT 50/50 the day before next bloods for sure

Daily, I prefer to take NDT 100% in one go

Usually in the morning, but occasionally in the evening

Is there a best time to take NDT, if you don't split?

Thanks again

Alps

[SlowDragon Administrator in reply to Hidden]

Sorry long time since I took NDT ...though I did always split it am and pm

I take levothyroxine once a day (bedtime) and split dose T3 - as 3 small doses at 8 hour intervals

[Hidden in reply to SlowDragon]

Thank you

[Hidden in reply to SlowDragon]

Hi slowdragon

Thanks for your tips

Would you know if there is a HU/ Bloods forum please?

Thanks

Alps

[SlowDragon Administrator in reply to Hidden]

No sorry don’t know

[SlowDragon Administrator]

Low neutrophils can be linked to being hypothyroid, especially autoimmune

healthline.com/health/neutr...

whitelotusclinic.ca/blog/dr...

[Hidden in reply to SlowDragon]

Thanks slowdragon

Interesting link you have provided

Which suggests that low neutrophils is linked with hypo

Also suggests trying zinc, selenium and C, which I do

Thanks

Alps