This is interesting: medpagetoday.com/hematology...
"WASHINGTON -- The FDA approved selpercatinib (Retevmo) as the first specific treatment for metastatic non-small cell lung cancer (NSCLC) or thyroid cancer with rearranged during transfection (RET) gene fusions.
A selective inhibitor of the RET kinase, selpercatinib received the indication through FDA's accelerated approval process, which requires the sponsor, Eli Lilly, to conduct additional studies to confirm the safety and efficacy of the drug as a condition of final approval."