T3+T4 combo: Just wondering if anyone is on a... - Thyroid UK

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T3+T4 combo

vooxxy profile image
8 Replies

Just wondering if anyone is on a combo where they take more t3 than t4?

I did try this out with my endo two years ago I think it was 20 mg T3 and 50 mg T4 something like that it felt amazing the first like 5 days then it just went downhill again with feeling poor. My endo was slowly decreasing the t3 and upping the t4 so i guess when i had more t4 in my system it didnt agree with me.

So maybe i just needed a little bit of T4 alongside my regular dose of t3 30 mg which iam on just now. My results are t3 are just in the upper range and tsh 2.0 no thyroid took before blood test. My endo is willing to try that out maybe split a 25mg t4 and take half at first to see if i can get that great feeling back.

From what I see a lot of people take way more t4 than t3 when a combo just wondering if anyone is doing the opposite more t3 than t4? and how it is for you?

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SeasideSusie profile image
SeasideSusieRemembering

vooxxy

If your TSH is 2.0 then you are undermedicated whatever combination you are on.

What are you actual results, with their reference ranges, please post them.

Exactly what thyroid meds do you take and when did you take your last dose before testing?

What are your current levels for Vit D, B12, Folate, Ferritin and are you taking any supplements?

vooxxy profile image
vooxxy in reply to SeasideSusie

Thanks for the Reply I i will get the ranges of what i got tested soon i need to get a new printout of them.

greygoose profile image
greygoose

it felt amazing the first like 5 days then it just went downhill again with feeling poor.

Perfectly normal. It just meant you needed and increase in dose - probably in T3 - that's the way it works, but doctors just don't seem to know that.

vooxxy profile image
vooxxy in reply to greygoose

Same old story with Drs but I do feel these endos are willing to work with me rather than against like some i have came across

greygoose profile image
greygoose in reply to vooxxy

Being willing to work with you is not the same thing as knowing what they're doing. Sounds to me as if your endo went into panic mode after your symptoms came back and started wildly thrashing about with the dose, and grasping at straws. It would have been sufficient to just increase your dose of T3. :)

Zephyrbear profile image
Zephyrbear

I have been allowed to pretty much set my own dosage of T3/T4 combo under my endo’s supervision since I was put on it in 2011. My old endo was wonderful, always listened to how I felt backed up by a blood test rather than the other way around and he gave me the freedom to take what worked for me. By the time he retired we’d worked our way through some ups and downs and reached a level plateau. I also educated myself (the absence of brain fog made that so much easier) and, despite their best efforts, no other endo has been able to sway me since. I am now on 25mcg of T4 with 50mcg of T3 daily, my TSH is unmeasurable and my FT4 results have been around the 6.8 mark for years, but my FT3 results have always been near the top of the range... and I feel fine! So, yes, some of us find ourselves doing much better on a higher dose of T3 to T4 ratio. The only way to find out if you’re one of us is to play around until you feel consistently well, but don’t try to do it all at once. Small adjustments and give them time to work... Good luck.

vooxxy profile image
vooxxy in reply to Zephyrbear

Very interesting thanks for the reply nice to know there are those out there with this ratio rather then the other way around.

"it felt amazing the first like 5 days then it just went downhill again with feeling poor"

I panicked a bit when that happened to me, but as greygoose said it is very common. You are likely to find the same with every increase until you get to the right level. The main thing is to take it slowly and gradually on every change. Our bodies can't easily cope with constant ups and downs of thyroid replacement - too much of a shock to the system

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