Elevated anti thyroid peroxidase : What does... - Thyroid UK

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Elevated anti thyroid peroxidase

Maggiemay12 profile image
18 Replies

What does elavated anti thyroid peroxidase antibody levels (179i/ u/ lml .

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Maggiemay12
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18 Replies
SeasideSusie profile image
SeasideSusieRemembering

Raised thyroid peroxidase antibodies suggest autoimmune thyroid disease aka Hashimoto's.

Is this the first time they've been tested?

Maggiemay12 profile image
Maggiemay12 in reply toSeasideSusie

Yes ,been on levothyroxine for maybe 10 years but endocrinologist wants me to up them but when I do I’m I’ll as in feel terrible and joints inflamed and sinuses sore

SeasideSusie profile image
SeasideSusieRemembering in reply toMaggiemay12

Maggiemay12

How much Levo are you taking?

What are you current test results for

TSH

FT4

FT3

and because Hashi's tends to lead to low nutrient levels, often due to gut/absorption problems that Hashi's can cause, it's also important to test:

Vit D

B12

Folate

Ferritin

General Hashi's information:

Hashi's is where the thyroid is attacked by the immune system and gradually destroyed. Fluctuations in symptoms and test results are common with Hashi's.

Most doctors dismiss antibodies as being of no importance and know little or nothing about Hashi's and how it affects the patient, test results and symptoms. You need to read, learn, understand and help yourself where Hashi's is concerned.

Some members have found that adopting a strict gluten free diet can help, although there is no guarantee.

Gluten contains gliadin (a protein) which is thought to trigger autoimmune attacks so eliminating gluten can help reduce these attacks.

You don't need to be gluten sensitive or have Coeliac disease for a gluten free diet to help.

Gluten/thyroid connection: chriskresser.com/the-gluten...

stopthethyroidmadness.com/h...

stopthethyroidmadness.com/h...

hypothyroidmom.com/hashimot...

thyroiduk.org.uk/tuk/about_...

Supplementing with selenium l-selenomethionine 200mcg daily can also help reduce the antibodies, as can keeping TSH suppressed.

Maggiemay12 profile image
Maggiemay12 in reply toSeasideSusie

TSH in June first thing in morning was 4.81 ,T3 3.6 , T4 20.1 but when endocrinologist did them this month in afternoon they were TSH 3.43 , free T3 4.0 and waiting on TSH receptor antibody still waiting on that result

SeasideSusie profile image
SeasideSusieRemembering in reply toMaggiemay12

To interpret your results we need reference ranges please - usually at the side of the result, possibly in brackets.

TSH receptor antibodies test for Graves disease - overactive thyroid - was this mentioned, is Graves being considered then?

Have you seen the results for vitamins? Fine just means somewhere in range but doesn't necessarily mean they are at optimal levels.

Maggiemay12 profile image
Maggiemay12 in reply toSeasideSusie

All vitamins were tested and fine

Nanaedake profile image
Nanaedake in reply toMaggiemay12

Don't rely on the word, fine. Get the results and post here for advice. Fine can mean at bottom of range and that won't make you feel well.

Maggiemay12 profile image
Maggiemay12 in reply toNanaedake

TSH levels was 4.81 ,range is 0.27 -4.21 .T4 was 20.1 range was 12-22 .T3 3.61 range is 3.1-6.8

Nanaedake profile image
Nanaedake in reply toMaggiemay12

Oh, I was referring to vitamin levels.

Maggiemay12 profile image
Maggiemay12 in reply toNanaedake

The haemoglobin was near the top off the range .B12 was same near top of range .Vit D haven’t got done but in pass it was good

SeasideSusie profile image
SeasideSusieRemembering in reply toMaggiemay12

Was ferritin tested? Or an Iron panel? Folate?

Vit D haven’t got done but in pass it was good

What was "good", what was the level. And it doesn't mean it still good now.

Maggiemay12 profile image
Maggiemay12 in reply toMaggiemay12

Sorry range for T4 was 10.6 -23.2 .

SeasideSusie profile image
SeasideSusieRemembering in reply toMaggiemay12

TSH levels was 4.81 ,range is 0.27 -4.21

T4 was 20.1 range was 10.6 -23.2

T3 3.61 range is 3.1-6.8

Well, your results are unusual in that your FT4 is in the upper part of the range at 75% of the way through and your TSH is also high. One would expect a much lower TSH with your FT4 level. However, your raised TPO antibodies suggest Hashi's and this can bring strange results.

So what's the reason to test TSH receptor antibodies? As mentioned this tests for Graves disease (overactive thyroid) and with an over range TSH there's no way that suggests Graves.

Maggiemay12 profile image
Maggiemay12 in reply toSeasideSusie

It’s because when I try to increase levothyroxine I feel worse ,I can only increase by a tiny bit once a week as I just feel inflamed in hands and joints and brain fog etc .I use to be on 75 but can’t tolerate that amount anymore .Maybe it’s the sea air as some believe you absorb more iodine from sea air !!!

SeasideSusie profile image
SeasideSusieRemembering in reply toMaggiemay12

Maybe it’s the sea air as some believe you absorb more iodine from sea air !!!

I think you'd need to be living in a coastal seaweed hotspot for iodine intake through respiration to make a significant difference. I have lived at the seaside for 25 years, opposite the beach, and walk my dog on the beach most days, my iodine level was half way through the reference range when tested 3 years ago.

What are your levels of Ferritin, Folate, B12 and Vit D.

What brand of Levo do you take? Has this been changed at all?

Maggiemay12 profile image
Maggiemay12 in reply toSeasideSusie

I use wockhard brand .hope I’ve spelt it correctly.i use a different brand years ago Avis I think but it started to disagree with me

SeasideSusie profile image
SeasideSusieRemembering in reply toMaggiemay12

What are your levels of Ferritin, Folate, B12 and Vit D.

Maggiemay12 profile image
Maggiemay12 in reply toSeasideSusie

Seeing someone that does muscle testing that highly recommend to test for these as I said before the ferritin folate and B12 were near the top range .

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