Why is T3 in short supply?: Clearly people are... - Thyroid UK

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Why is T3 in short supply?

Coppernob profile image
23 Replies

Clearly people are experiencing difficulties in obtaining T3 at present. I'm not asking where to get some. What I'm asking is why does the supply seem to be drying up? All of us on T3 only depend on this drug being continuously available.

Can anyone explain this shortage, which appears to be general, not limited to one supplier?

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Coppernob profile image
Coppernob
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23 Replies
shaws profile image
shawsAdministrator

That's what all of us woud like to know. I hope someone has the answer.

It's not only the supply that is a problem but the now exorbitant prices being asked.Many suppliers seem to have jumped on the band-wagon.

EbonyEvans profile image
EbonyEvans

My supplier - legit pharmacist explained it as people have stocked up and are being caught by the authorities with large quantities of stock. She assumes the stock is destroyed and pharmaceutical companies being warned to stop selling so freely. Greece have more stringent checks in place now. IE prescription needed in most islands. Most of EU countries have daily deliveries unlike the U.K. so it’s not possible to bulk buy stock as there’s no storage space and it would flag up now.

She’s also said there’s no Cynomel due to an ebb in orders so production isn’t warranted as most Mexicans don’t need Cynomel (🤷🏾‍♀️)

Trixie64 profile image
Trixie64

I've been told that Grossman will give an update about Cynomel after 15th November. Don't know any more.

EbonyEvans profile image
EbonyEvans in reply to Trixie64

I heard similar.

JudithW profile image
JudithW in reply to Trixie64

<A pharmacy > told me Grossman had moved, and were waiting for the licence to restart production. The last information I had was

Hi Judith

Unfortunately Grossman-Valenat have not told us anything yet, their saying they will advise at the end of this month, hopefully with very good news, you can contact me through this email in a couple of weeks to see how it goes.

Trixie64 profile image
Trixie64 in reply to JudithW

Thanks JudithW. Let's keep hoping!

Marz profile image
Marz

Maybe looking back at history is helpful. There was a time when everyone took NDT - until Big Pharma created T4 and Doctors were 'persuaded' to chage over. Apparently T4 was all you needed ! Keeping patients sub-optimal creates many conditions that need various treatments - bolstering the turnover for BP.

Now we cannot have people getting well on T3 can we ?

overnighthearingloss profile image
overnighthearingloss in reply to Marz

That's so cynical, but??

Marz profile image
Marz in reply to overnighthearingloss

How could the whole world of medicine be persuaded that NDT was wrong - T4/Levo was right - unless there were inducements ... obviously the health of the patient was of no interest. Then along came Fibro/CFS/ME ...

overnighthearingloss profile image
overnighthearingloss in reply to Marz

same with vitamin c. Been having that discussion over on the lupus forum

As the Goldman Sachs spokesman said...there no money in cures.

JudithW profile image
JudithW in reply to Marz

Since I have been on T3 my blood pressure has gone down, I think it must be attributed to the fact that T3 reduces peripheral resistance hence lowering the blood pressure. Also I have skin colour changes on my lower leg, the sort of thing which can go into leg ulcers, this is diminishing after about 25 years. Inflammation has settled and proper skin colour is reappearing. I also think cholesterol is lowered with T3, someone mentioned this and certainly my cholesterol is 3.1 with the HDL good and high. Just think of all the money pharma would loose just on these factors alone. No wonder Concordia charged £800 per 100 tablets.

Marz profile image
Marz in reply to JudithW

So glad your health is so much better. I am constantly concerned at the multiple medications people take without knowing their T3 levels - doctor knows best. Keep up the good work 😊

JudithW profile image
JudithW in reply to Marz

Thanks Marz I am in the middle of a complaint to the Chief exec local hospital because the senior Endo has not responded to my letter x 2 asking for her clinical rationale as to why she says I do not need T3. Private 24 hour urine 292 (800-2500), breathing improved with T£ +++ other improvements.

JudithW profile image
JudithW in reply to JudithW

Just had a look at Concordia page the ones who make the T3 for UK

Concordia International Corp. Announces Third Quarter 2018 Results

Concordia International Corp.

Nov 14, 2018, 07:00 ET

Third quarter 2018 revenue of $128 million

Third quarter net income of $1.8 billion, which includes a $1.9 billion gain on debt settlement as part of the Company's recently completed transaction to realign its capital structure (the "Recapitalization Transaction")

Third quarter 2018 Adjusted EBITDA2 of $59 million

Generated cash flow from operations of $98 million in the first nine months of 2018 and concluded the third quarter of 2018 with a cash balance of $209 million

Jbold1 profile image
Jbold1 in reply to JudithW

You do realize this company makes a LOT of other things besides T3, right? Plus, you can't just copy and paste info without posting the source. You say "...look at Concordia 'page'...", like what does that even mean? What page? Are you looking at their organization's financial statements from the third quarter of 2018, which you could ONLY get from the Security Exchange Commission's site? Somehow, I doubt those are the ACTUAL numbers reported on the orgs financial statements, and if so, they don't reflect any or all of the T3 sales. So, what exactly is your point when it comes to Concordia? If you're going to go after big business, especially publicly traded ones, you might want to know a thing or two about it before spouting off next time. I'm all for taking them down, but you need to know how to do it first.

JudithW profile image
JudithW in reply to Jbold1

Yes jbold1 your perfectly right here is the link concordiarx.com/release/?id...

They focus on 'generic and legacy pharmaceutical products' and ' has a diversified portfolio of more than 200 established, off-patent products.' concordiarx.com/about-us/

Concordia is being looked at by the The Competition and Markets Authority theguardian.com/business/20...

I found this in emc (Electronic medicine compendium) medicines.org.uk/emc/medici...

4.1 Therapeutic indications

Liothyronine sodium tablets are qualitatively similar in biological action to thyroxine but the effect develops in a few hours and lasts for 24 to 48 hours after stopping the treatment.

This appears to have been written by Concordia and is inaccurate Thyroxine, T4 does not have a biological action similar to Liothyronine. T4 is inert and has to be deodinated to T3 for any action.

Seeing Jbold1 that you are very much on the ball, would you look at this page and comment on the second paragraph it appears to be a bit wrong to me. hormone.org/hormones-and-he...

I look forward to your comments.

Kind regards

Judith

JudithW profile image
JudithW in reply to Jbold1

Welcome to the Open Air Jbold pleased you have been able to join us, and I apologise that my post rankled with you. As you will have seen following my link it was the organisations financial page. Might I ask why you thought the only place they would be found is Security Exchange Commission's site, I am not au fait with that, and I like to learn.

JudithW profile image
JudithW in reply to Marz

Those things might be Marz, but I have breathing problems inability to loose weight low body temperature, which I think is due to the fact that I possibly have an emerging disease Morgellons Syndrome. It presents first as a skin problem (mine was lumps with gritty bits in them), but can affect most of the body systems. There is a thought that it might be a dermal presentation of Lymes disease. Trying to get Dermatologist to believe your not delusional is not an easy task as that's what it used to be thought as. People with Hypothyroidism are more likely to get it.

Marz profile image
Marz in reply to JudithW

It must be so stressful for you. Have you read the book - Impaired Sensitivity to Thyroid Hormone by Hugh Hamilton. Available on Kindle and an informative read ...

I wonder if it is a knock on effect of all the people who would have got it on prescription now sourcing from online pharmacies, plus manufacturers cutting back as there should be less demand as not allowed on prescription any more. You'd think that some enterprising manufacturer in Thailand or somewhere would jump into the gap

JudithW profile image
JudithW in reply to Angel_of_the_North

Drs can prescribe it if they feel there is a clinical need. Many of them are just hiding behind CCG's saying NO. Levo (T4) is fine for Primary Hypothyroidism. ie where the Thyroid gland is not working properly. When there is a conversion problem so either the D102 is not working, or T4 is being turned into rT3 then all the levo in the world would not help, in fact it might make the situation worse, as more T4 available might mean more rT3 to swamp what little T3 there is.

I have asked the head of the Endos at local hospital for her clinical rationale as to why she said I do not need T3 I sent my private test results (T3 292 (800-2500)) plus blood tests to show ratio T3:rT3 as well. I sent info twice, and when no response I have written to the chief exec with a complaint, which is where I am.

I have in front of me NHS Englands findings 30.11.17 they state that they recommend the prescribing of Liothyronine for any new patient should be initiated by a consultant Endo (looks like I have lost out here). Page 4 england.nhs.uk/wp-content/u...

I also have a copy of British Thyroid Association 18.10.18. Main point 'we wish to emphasise that any decision to stop T3 must be based on clinical Criteria ' the final lines says ' NHS England proposal driven by the enormous increase in the cost of T3 with such cost being quite disproportionate and unique to the UK in comparison to its cost in other European countries. We suggest that the NHS pursues alternative procurement strategies to reduce the current cost of prescribing T3.

british-thyroid-association...

bta_response_to_the_nhs_england_consultation_for_website.pdf

Hope this can help you all in someway.

Smart5353 profile image
Smart5353

Apparently it's relatively cheap and easy to make. There's huge corruption going on somewhere in my opinion. And no money in a cure of course

Hillwoman profile image
Hillwoman in reply to Smart5353

That was my understanding too.

There's something fundamentally odd about the diminishing supply. We need to know exactly who is applying pressure to whom out of the public gaze.

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