Confusing test results

[pj16]

Hi. I've recently been posting on PAS forum but on examining my recent blood tests I noticed a difference in thyroid function results. I have tried researching but am baffled. My GP has tested TSH and Free T4 many times since 2012 with results as follows

TSH

2012 1.23mu/L (0.2 - 4.5mu/L)

2013 1.66mu/L (0.20 - 4.50mu/L)

2013 1.35mu/L (0.20 - 4.50mu/L)

2014 1.06mu/L (0.20 - 4.50mu/L)

2015 1.77mu/L (0.20 - 4.50mu/L)

2016 1.87mu/L (0.20 - 4.50mu/L)

2017 2.10mu/L (0.20 - 4.50mu/L)

Jan 2018 1.99mu/L (0.20 - 4.50mu/L)

20th Sept 2018 2.32mu/L (0.20 - 4.50mu/L)

Free T4

2012 14.3 pmol/L (9 - 23 pmol/L)

2013 16.0 pmol/L (9 - 23)

2013 14.9 pmol/L (9 - 23)

2014 14.5 pmol/L (9 - 23)

2015 14.9 pmol/L (9 - 23)

2016 10.7 pmol/L (7.0 - 17.0 pmol/L)

2017 12.3 pmol/L (7.0 - 17.0)

Jan 2018 11.8 pmol/L (7.0 - 17.0)

20th September 2018 10.3 pmol/L (7.0 - 17.0)

This all seems fairly normal to me however my recent Medichecks thyroid results (26th September) are as follows:-

Thyroid Stimulating hormone 3.34 mIU/L (0.27 - 4.20)

Free Thyroxine 19.300 pmol/L (12.00 - 22.00)

It would seem that even though bloods taken by GP and Medichecks were only six days apart there seems to be a big increase in TSH and Free Thyroxine. Can anyone shed any light on why this could be?

[greygoose]

Did you not get FT3 and TPO/Tg antibodies tested? They might supply some answers.

[pj16 in reply to greygoose]

Hi greygoose. Thanks for your response. GP only tested TSH and FreeT4. Medichecks tested TSH, Free T4 and Free T3. I'm seriously considering getting TPO/Tg antibodies tested but I don't want to do this if it's not indicated by my results. If Medichecks results are correct at:-

Thyroid Stimulating hormone 3.34 mIU/L (0.27 - 4.20)

Free Thyroxine 19.300 pmol/L (12.00 - 22.00)

Free T3 at 4.99 pmol/L (3.10 - 6.8)

do these seem okay?

Apparently my Ferritin, vitamin D and serum B12 could be better also.

[greygoose in reply to pj16]

No, not ok at all. A TSH of over 3 is hypo - although not according to the rediculous ranges. Your FT4 is good, but it's not converting to T3, so your FT3 is not as high as it should be with that level of FT4.

[humanbean]

Time of day blood is taken will affect TSH - it has a circadian rhythm and is at its highest in the middle of the night. This is why people are advised to get blood tests done as early as possible in the morning.

See this post and the graphs for more info :

healthunlocked.com/thyroidu...

[pj16 in reply to humanbean]

Hi humanbean. Thanks for replying. Tests done by both GP and Medichecks (6 days apart) were done in the morning after fasting for approximately 13 hours.