Can Free T4 chop and change and cause change in symptoms?

[pj16]

Good evening all. I'm hoping some of you very knowledgeable members can answer a query for me. Is it possible for free T4 to vary a lot? I can't understand how, in the space of a couple of weeks mine has gone from 33% of range to 69% of range (using calculator at chorobytarczycy.eu/kalkulator). TSH continues to rise. I feel so much worse in recent months and some of my symptoms have changed. I only took the Medichecks test because I had only ever had antibodies checked once (last year) which showed raised thyroglobulin antibodies and I wanted to make sure it wasn't raised as a one off. I am not currently diagnosed or medicated.

17 Jan 2019 GP

Serum free T4 level 10.3 pmol/L (7.0 - 17.0)

Serum TSH level 3.35 mu/L (0.20 - 4.50)

12 Feb 2019 Medichecks

TSH 4.14 mIU/L (Range: 0.27 - 4.2)

Free T3 5.18 pmol/L (Range: 3.1 - 6.8)

Free T4 18.900 pmol/L (Range: 12 - 22)

Thyroglobulin Antibody 299.000 kU/L (Range: < 115)

Thyroid Peroxidase Antibodies <9.0 kIU/L (Range: < 34)

Thanks for reading.

[Greybeard]

I expect these are the key.

Thyroglobulin Antibody 299.000 kU/L (Range: < 115

When your thyroid is under attack from your immune system t4 and t3 is dumped into your system as throid cells are destroyed.

[pj16 in reply to Greybeard]

Thanks for that. I think I understand what you're saying. So free T4 and T3 levels can fluctuate depending on severity of attack from antibodies so to speak?

[SlowDragon Administrator]

A month ago your vitamin levels were low

healthunlocked.com/thyroidu...

Vitamin D, Ferritin, B12 and folate were all low

Have you been working on improving these ?

Your TSH is rising, but you may struggle to get any medics to treat yet.

[pj16 in reply to SlowDragon]

Hi SlowDragon. Thanks for your response. Yes I have. I've increased vitamin D (Better You spray with K2) to 5000 (5 sprays). I've started Jarrows B12 sublingual. I'm making sure to eat red meat once a week otherwise chicken, fish etc. and plenty of veg. Also eating chicken liver pate which is the best I can do as eating actual liver is a step too far for me! I'm making progress with gluten free but far from perfect yet! I'll reply now to your reply to my other post you mention.

[Hidden]

Can you repost the calculator ?

[pj16 in reply to Hidden]

chorobytarczycy.eu/kalkulator

[vocalEK in reply to pj16]

Cool. Mine came out to FT4 at 81.82% and FT3 at -36.02%, demonstrating a clear problem with conversion. Thankfully, my PCP (a GP) has prescribed T3.