No idea why my results swing so much

[MCP80]

On 19 April my results were:

TSH 0.53 (0.27-4.5)

FT4 25.7 (11-23)

FT3 4.53 (3.1-6.8)

Results from 11 May

TSH 59.3 (0.27-4.5)

FT4 14.9 (11-23)

FT3 3.37 (3.1-6.8)

I am on 150mg per day Eltroxin and all my other blood work I am happy with as I take quite a lot of supplements but know when to take them as not to interfere withe the Thyroxin.

I was diagnosed in 2005 and borderline for 12-14 years before that.

I have been with an endocrinologist for the last year and I am still no further forward at trying to get to the bottom as to why my levels swing so much.

I wasn't expecting the results I received today and was just hoping that I had similar results to Aprils blood results so I can try and prove I was not converting very well.

I have missed a few tablets in the last 6 weeks here and there but no way near enough to cause those results.

Has anyone experienced a similar case to me where your levels do not stay stable at any point?

Would anyone have any advice on what to try next to get them to stabilise please?

I am already strictly Gluten and Lactose free and monitor my vitamin and mineral levels by taking supplements but I am now at a loss as to what to do next.

Thank you x

[greygoose]

Are they NHS tests?

Have you had antibodies tested?

Do you take biotin in any of your supplements, and did you take it on the day of the blood draw?

[MCP80 in reply to greygoose]

Hi greygoose,

Yes they are NHS. I haven't had an antibodies test for a number of years but I have hereditary Hashimotos.

No I don't take any biotin.

36 hours clear of any Thyroxin or supplements at 0820, fasting with a pint of water after I got up.

[greygoose in reply to MCP80]

36 hours is too long. You shouldn't leave more than 24 hours.

Is that for both of them? Both a gap of 36 hours and blood draw at 8.20?

If you know you have Hashi's, there's no need to retest antibodies, you will always have Hashi's. And Hashi's could be responsible for the change in levels... But I'm not convinced. I don't know, I'm afraid.

[MCP80 in reply to greygoose]

It was only 36 hours as I take my tablets at night. So maybe more like 33-34 hours.

I was very suprised today when I rung up for the results as my last lot were only just over 3 weeks ago.

I did have an extremely busy week last week but even then it wouldn't use that amount of Thyroxin. I was trying to prove a permanent low T3 result as my consultant was considering a trial of T3 tablets to try and get rid of my Hypo symptoms even with in rage TSH and high T4.

They can't figure it out either.

Thank you for replying.

[greygoose in reply to MCP80]

No, I don't suppose they can! I wouldn't have thought that it was possible for a TSH to go from low normal to very, very high in the space of one month, because it doesn't move that fast. Or your FT4 to go from well over-range to low normal without a change of dose. So, although there is a possibility that the Hashi's is to blame, I would also strongly consider laboratory error. There have been a spate of such results, recently. Although one never used to see such things. So, I can't help wondering if there is a problem with the machines being used these days. But, I don't know how you'd prove it.