I read an article in a magazine at the Doc's yesterday which stated that a large percentage of Hypo sufferers also suffer from depression - cannot remember the mag or the statistics but I wondered if that was true? I know that in my case, I have found for the past few years that I (and there is not an easy way to explain this) have the 'top layer of happiness' missing!! If you could measure happiness as a percentage, I would say I was at 80% - does this mean low grade depression?? I have a good life, look after myself with GF diet, take all the supplements necessary, do not eat processed food, juice every day - in short, do all I can to keep healthy. I have 4 lovely grandchildren and at 61, have been retired (through choice) for a few years and yet......... My recent blood test showed my T3 as 3.78 (3.10 - 6.80) (I had a private test done and stupidly took a small does of levo the night before because I didn't know for sure I would be able to get blood drawn that day - not sure if that would make a difference up or down) Sooo, would NDT make a difference to my happiness level do you think, or would there be something else at play - are we all destined to feel bleugh for life??